miRBase entry: ppy-mir-141

Stem-loop ppy-mir-141

Accession

MI0002489

Description

Pongo pygmaeus ppy-mir-141 precursor miRNA

Sequence

uggccggcccuggguucaucuuccaguacaguguuggauggucuaauugugaagcuccuAACACUGUCUGGUAAAGAUGGcccccggguggguuc
.((((.((((.(((.(((((((((((.(((((((((((...((.......))...))).))))))))))))..))))))).))).)))).)))).

Structure

u    g    u   u       --    u        -   ugg  ua 
 ggcc gccc ggg ucaucuu  ccag acaguguu gga   uc  a
 |||| |||| ||| |||||||  |||| |||||||| |||   ||  u
 uugg uggg ccc GGUAGAA  GGUC UGUCACAA ccu   ag  u
c    g    c   c       AU    -        u   cga  ug

Annotation confidence Not enough data

Do you think this miRNA is real?

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr12: 7200096-7200190 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from ppy-mir-141

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature ppy-miR-141

Accession	MIMAT0002200
Description	Pongo pygmaeus ppy-miR-141 mature miRNA
Sequence	60 - AACACUGUCUGGUAAAGAUGG - 80
Evidence	not_experimental

References

PubMed ID: 15652478
Phylogenetic shadowing and computational identification of human microRNA genes
"Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
"Cell (2005) 120:21-24