Stem-loop mml-mir-29a

Accession

MI0002662

Description

Macaca mulatta mml-mir-29a precursor miRNA

Literature search

6 open access papers mention mml-mir-29a
(7 sentences)

Sequence

610471 reads, 4251 reads per million, 8 experiments

augaCUGAUUUCUUUUGGUGUUCAGAgucaauauaauuuuCUAGCACCAUCUGAAAUCGGUUau
((((((((((((...(((((((.((((...........)))))))))))...))))))))))))

Structure

            UUU       C    ucaa 
augaCUGAUUUC   UGGUGUU AGAg    u
||||||||||||   ||||||| ||||    a
uaUUGGCUAAAG   ACCACGA UCuu    u
            UCU       -    uuaa 

Annotation confidence Medium

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr3: 157003023-157003086 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-29a

Mature mml-miR-29a-3p

• Accession: MIMAT0002365
• Description: Macaca mulatta mml-miR-29a-3p mature miRNA
• Sequence: 41 - CUAGCACCAUCUGAAAUCGGUU - 62
• Evidence: experimental ; Illumina [2]

Mature mml-miR-29a-5p

• Accession: MIMAT0026576
• Description: Macaca mulatta mml-miR-29a-5p mature miRNA
• Sequence: 5 - CUGAUUUCUUUUGGUGUUCAGA - 26
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45