Stem-loop mml-mir-34a

Accession

MI0002801

Description

Macaca mulatta mml-mir-34a precursor miRNA mir-34

Gene
family

RF00456; mir-34

Literature search

24 open access papers mention mml-mir-34a
(63 sentences)

Sequence

72828 reads, 232.0 reads per million, 150 experiments

ggccagcugugaguguuucuuUGGCAGUGUCUUAGCUGGUUGUUgugagcaauaguaaggaagCAAUCAGCAAGUAUACUGCCCUagaagugcuacacauuguggggccu
((((.(((((((((((((((..(((((((((((.((((((((((....((....)).....))))))))))))).))))))))..))))))))).))))..))..)))).

Structure

-    -a  --    -         uU        -   A          -guga  a 
 ggcc  gc  ugug aguguuucu  GGCAGUGU CUU GCUGGUUGUU     gc a
 ||||  ||  |||| |||||||||  |||||||| ||| ||||||||||     ||  
 ccgg  ug  acac ucgugaaga  CCGUCAUA GAA CGACUAACga     ug u
u    gg  uu    a         UC        U   -          aggaa  a 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

1: 215342661-215342770 [+]

Mature mml-miR-34a-5p

• Accession: MIMAT0002499
• Description: Macaca mulatta mml-miR-34a-5p mature miRNA
• Sequence: 22 - UGGCAGUGUCUUAGCUGGUUGUU - 44
• Evidence: experimental ; Illumina [2]

Mature mml-miR-34a-3p

• Accession: MIMAT0026586
• Description: Macaca mulatta mml-miR-34a-3p mature miRNA
• Sequence: 64 - CAAUCAGCAAGUAUACUGCCCU - 85
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45