Stem-loop mml-mir-182

Accession

MI0002815

Description

Macaca mulatta mml-mir-182 precursor miRNA mir-182

Gene
family

RF00702; mir-182

Literature search

10 open access papers mention mml-mir-182
(16 sentences)

Sequence

2000198 reads, 1174.0 reads per million, 153 experiments

cacagcugcuugccucccccuguuUUUGGCAAUGGUAGAACUCACACUggugagguaaugggauccGGUGGUUCUAGACUUGCCAACUacggggcgagggcucagccggcac
....((((((.((((.(((((((..(((((((...((((((...((((((..............))))))))))))...)))))))..)))))).).))))..)).))))..

Structure

caca    -  -u    c -      uU       UGG      UCA      ugaggu 
    gcug cu  gccu c cccugu  UUGGCAA   UAGAAC   CACUgg      a
    |||| ||  |||| | ||||||  |||||||   ||||||   ||||||       
    cggc ga  cggg g ggggca  AACCGUU   AUCUUG   GUGGcc      a
--ca    c  cu    a c      UC       CAG      ---      uagggu 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

3: 156048364-156048475 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mml-mir-182

Mature mml-miR-182-5p

• Accession: MIMAT0002513
• Description: Macaca mulatta mml-miR-182-5p mature miRNA
• Sequence: 25 - UUUGGCAAUGGUAGAACUCACACU - 48
• Evidence: not_experimental

Mature mml-miR-182-3p

• Accession: MIMAT0051605
• Description: Macaca mulatta mml-miR-182-3p mature miRNA
• Sequence: 67 - GGUGGUUCUAGACUUGCCAACU - 88
• Evidence: not_experimental

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24