Stem-loop mml-mir-214

Accession

MI0002858

Description

Macaca mulatta mml-mir-214 precursor miRNA

Literature search

1 open access papers mention mml-mir-214
(1 sentences)

Sequence

1551 reads, 21 reads per million, 8 experiments

ggccuggcuggacagaguugucaugugucUGCCUGUCUACACUUGCUGUGCagaacauccgcucaccuguACAGCAGGCACAGACAGGCAGucacaugacaacccagccu
.....((((((.....(((((((((((.((((((((((...((((((((((((.............))))))))))))...)))))))))).))))))))))))))))).

Structure

ggccu      acaga           u          ACA            aacau 
     ggcugg     guugucaugug cUGCCUGUCU   CUUGCUGUGCag     c
     ||||||     ||||||||||| ||||||||||   ||||||||||||     c
     ccgacc     caacaguacac GACGGACAGA   GGACGACAuguc     g
----u      -----           u          CAC            cacuc 

Annotation confidence Medium

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr1: 195417710-195417819 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-214

Mature mml-miR-214-3p

• Accession: MIMAT0002555
• Description: Macaca mulatta mml-miR-214-3p mature miRNA
• Sequence: 71 - ACAGCAGGCACAGACAGGCAG - 91
• Evidence: experimental ; Illumina [2]

Mature mml-miR-214-5p

• Accession: MIMAT0026588
• Description: Macaca mulatta mml-miR-214-5p mature miRNA
• Sequence: 30 - UGCCUGUCUACACUUGCUGUGC - 51
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45