Stem-loop mml-mir-224

Accession

MI0002903

Description

Macaca mulatta mml-mir-224 precursor miRNA

Literature search

4 open access papers mention mml-mir-224
(6 sentences)

Sequence

145987 reads, 633.0 reads per million, 133 experiments

gggcuuuCAAGUCACUAGUGGUUCCGUUUAGUagaugauugugcauuguuucaAAAUGGUGCCCUAGUGACUACAaagccc
(((((((..(((((((((.(((.((((((.(.(((((((.....)))))))).)))))).))))))))))))..)))))))

Structure

       CA         U   U      A U       u 
gggcuuu  AGUCACUAG GGU CCGUUU G agaugau g
|||||||  ||||||||| ||| |||||| | ||||||| u
cccgaaA  UCAGUGAUC CCG GGUAAA c uuuguua g
       CA         -   U      a -       c 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

X: 147965325-147965405 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-224

Mature mml-miR-224-5p

• Accession: MIMAT0002594
• Description: Macaca mulatta mml-miR-224-5p mature miRNA
• Sequence: 8 - CAAGUCACUAGUGGUUCCGUUUAGU - 32
• Evidence: experimental ; Illumina [2]

Mature mml-miR-224-3p

• Accession: MIMAT0026591
• Description: Macaca mulatta mml-miR-224-3p mature miRNA
• Sequence: 54 - AAAUGGUGCCCUAGUGACUACA - 75
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45