Stem-loop mml-mir-15a

Accession

MI0002957

Description

Macaca mulatta mml-mir-15a precursor miRNA

Literature search

11 open access papers mention mml-mir-15a
(19 sentences)

Sequence

359851 reads, 613.0 reads per million, 149 experiments

ccuuggaguaaagUAGCAGCACAUAAUGGUUUGUGGAuuuugaaaaggugCAGGCCAUAUUGUGCUGCCUCaaaaauacaagg
(((((.......(..((((((((..((((((((((.............))))))))))..))))))))..).......)))))

Structure

     gaguaaa UA        UA          GAuuu 
ccuug       g  GCAGCACA  AUGGUUUGUG     u
|||||       |  ||||||||  ||||||||||     g
ggaac       C  CGUCGUGU  UACCGGACgu     a
     auaaaaa UC        UA          ggaaa 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

17: 28503483-28503565 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mml-mir-15a

Mature mml-miR-15a-5p

• Accession: MIMAT0002650
• Description: Macaca mulatta mml-miR-15a-5p mature miRNA
• Sequence: 14 - UAGCAGCACAUAAUGGUUUGUGGA - 37
• Evidence: experimental ; Illumina [2]

Mature mml-miR-15a-3p

• Accession: MIMAT0026593
• Description: Macaca mulatta mml-miR-15a-3p mature miRNA
• Sequence: 51 - CAGGCCAUAUUGUGCUGCCUC - 71
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45