miRBase entry: mml-mir-92a-1

Stem-loop mml-mir-92a-1

Accession

MI0003006

Description

Macaca mulatta mml-mir-92a-1 precursor miRNA

Literature search

2 open access papers mention mml-mir-92a-1
(8 sentences)

Sequence

97717 reads, 996 reads per million, 8 experiments

cuuucuacacagguugggaucgguugcaaugcuguguuucuguauggUAUUGCACUUGUCCCGGCCUGUugaguuugg
....((..((((((((((((.(((.(((((((((((......)))))))))))))).))))))))))))..)).....

Structure

-cuuu  ac            c   u           uu 
     cu  acagguugggau ggu gcaaugcugug  u
     ||  |||||||||||| ||| |||||||||||   
     ga  UGUCCGGCCCUG UCA CGUUAUgguau  c
gguuu  gu            U   -           gu

Annotation confidence Medium

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Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context

chr17: 73096816-73096893 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from mml-mir-92a-1

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature mml-miR-92a-3p

Accession	MIMAT0002706
Description	Macaca mulatta mml-miR-92a-3p mature miRNA
Sequence	48 - UAUUGCACUUGUCCCGGCCUGU - 69
Evidence	experimental Illumina [2]
Database links
Predicted targets

References

PubMed ID: 15345052
Microarray analysis of microRNA expression in the developing mammalian brain
Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
Genome Biol (2004) 5:R68

PubMed ID: 15652478
Phylogenetic shadowing and computational identification of human microRNA genes
"Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
"Cell (2005) 120:21-24