Stem-loop mml-mir-23a

Accession

MI0003051

Description

Macaca mulatta mml-mir-23a precursor miRNA

Literature search

14 open access papers mention mml-mir-23a
(22 sentences)

Sequence

2210090 reads, 4835.0 reads per million, 153 experiments

ggccggcuGGGGUUCCUGGGGAUGGGAUUUgcuuccugucacaaAUCACAUUGCCAGGGAUUUCCAaccgacc
((.(((.((((((((((((.((((.((((((..........)))))).)))).))))))).))))).))).))

Structure

  c   c     -       G    G      cuuc 
gg cgg uGGGG UUCCUGG GAUG GAUUUg    c
|| ||| ||||| ||||||| |||| ||||||     
cc gcc ACCUU AGGGACC UUAC CUAaac    u
  a   a     U       G    A      acug 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

19: 13435736-13435808 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mml-mir-23a

Mature mml-miR-23a-5p

• Accession: MIMAT0026599
• Description: Macaca mulatta mml-miR-23a-5p mature miRNA
• Sequence: 9 - GGGGUUCCUGGGGAUGGGAUUU - 30
• Evidence: experimental ; Illumina [2]

Mature mml-miR-23a-3p

• Accession: MIMAT0002752
• Description: Macaca mulatta mml-miR-23a-3p mature miRNA
• Sequence: 45 - AUCACAUUGCCAGGGAUUUCCA - 66
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45