Stem-loop mml-mir-183

Accession

MI0003084

Description

Macaca mulatta mml-mir-183 precursor miRNA mir-183

Gene
family

RF00663; mir-183

Literature search

1 open access papers mention mml-mir-183
(3 sentences)

Sequence

38360 reads, 296 reads per million, 8 experiments

ccgcagaacgugacuccuguucugugUAUGGCACUGGUAGAAUUCACUGugaacagucucggucaGUGAAUUACCGAAGGGCCAUAAAcagagcagagacagauccacga
........((((..(((((((((((.((((((.((((((..(((((((((((......)))..))))))))))))..)).)))))).))))))))).....))..)))).

Structure

ccgcagaa    ac  -----         g      A  --    GA        --   ac 
        cgug  uc     cuguucugu UAUGGC CU  GGUA  AUUCACUG  uga  a
        ||||  ||     ||||||||| |||||| ||  ||||  ||||||||  |||   
        gcac  ag     gacgagacA AUACCG GA  CCAU  UAAGUGac  gcu  g
-------a    cu  acaga         A      G  AG    --        ug   cu 

Annotation confidence Medium

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr3: 155860330-155860439 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mml-mir-183

Mature mml-miR-183-5p

• Accession: MIMAT0002783
• Description: Macaca mulatta mml-miR-183-5p mature miRNA
• Sequence: 27 - UAUGGCACUGGUAGAAUUCACUG - 49
• Evidence: experimental ; Illumina [2]

Mature mml-miR-183-3p

• Accession: MIMAT0026603
• Description: Macaca mulatta mml-miR-183-3p mature miRNA
• Sequence: 66 - GUGAAUUACCGAAGGGCCAUAAA - 88
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45