Stem-loop hsa-mir-519a-2

Accession

MI0003182

Symbol

HGNC: MIR519A2

Description

Homo sapiens hsa-mir-519a-2 precursor miRNA mir-515

Gene
family

RF00639; mir-515

Literature search

34 open access papers mention hsa-mir-519a-2
(226 sentences)

Sequence

148 reads, 2 reads per million, 24 experiments

ucucaggcugugucCCUCUACAGGGAAGCGCUUUCuguugucugaaagaaaggAAAGUGCAUCCUUUUAGAGUGUuacuguuugaga
((((((((.(((.(.(((((.(((((.(((((((((....(((...)))..))))))))).))))).))))).).))).))))))))

Structure

        u   u C     C     A         guug   g 
ucucaggc gug c CUCUA AGGGA GCGCUUUCu    ucu  
|||||||| ||| | ||||| ||||| |||||||||    ||| a
agaguuug cau G GAGAU UUCCU CGUGAAAgg    aga  
        u   U U     U     A         --aa   a 

Annotation confidence High

Genome context

chr19: 53762344-53762430 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from hsa-mir-519a-2

Disease association

hsa-mir-519a-2 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-519a-3p

• Accession: MIMAT0002869
• Description: Homo sapiens hsa-miR-519a-3p mature miRNA
• Sequence: 54 - AAAGUGCAUCCUUUUAGAGUGU - 75
• Evidence: experimental ; array-cloned [1], cloned [2]

Mature hsa-miR-519a-2-5p

• Accession: MIMAT0037327
• Description: Homo sapiens hsa-miR-519a-2-5p mature miRNA
• Sequence: 15 - CCUCUACAGGGAAGCGCUUUC - 35
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15965474
   Identification of hundreds of conserved and nonconserved human microRNAs
   "Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z"
   "Nat Genet (2005) 37:766-770


3. PubMed ID: 25822230
   Selective microRNA-Offset RNA expression in human embryonic stem cells
   Asikainen S, Heikkinen L, Juhila J, Holm F, Weltner J, Trokovic R, Mikkola M, Toivonen S, Balboa D, Lampela R, Icay K, Tuuri T, Otonkoski T, Wong G, Hovatta O
   PLoS One (2015) 10:e0116668