Stem-loop hsa-mir-532

Accession

MI0003205

Symbol

HGNC: MIR532

Description

Homo sapiens hsa-mir-532 precursor miRNA mir-532

Gene
family

RF04284; mir-532

Literature search

51 open access papers mention hsa-mir-532
(187 sentences)

Sequence

63669 reads, 406 reads per million, 133 experiments

cgacuugcuuucucuccucCAUGCCUUGAGUGUAGGACCGUuggcaucuuaauuacCCUCCCACACCCAAGGCUUGCAgaagagcgagccu
......((((.((((.((.((.((((((.((((.(((..((.............))..))).)))).)))))).)).)).)))).))))..

Structure

cgacuu    u    c  c  U      A    A   CC  uggca 
      gcuu cucu cu CA GCCUUG GUGU GGA  GU     u
      |||| |||| || || |||||| |||| |||  ||     c
      cgag gaga gA GU CGGAAC CACA CCU  ca     u
----uc    c    a  C  U      C    C   CC  uuaau 

Annotation confidence High

Genome context

chrX: 50003148-50003238 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from hsa-mir-532

Disease association

hsa-mir-532 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-532-5p

• Accession: MIMAT0002888
• Description: Homo sapiens hsa-miR-532-5p mature miRNA
• Sequence: 20 - CAUGCCUUGAGUGUAGGACCGU - 41
• Evidence: experimental ; PCR [1], cloned [2-3]

Mature hsa-miR-532-3p

• Accession: MIMAT0004780
• Description: Homo sapiens hsa-miR-532-3p mature miRNA
• Sequence: 57 - CCUCCCACACCCAAGGCUUGCA - 78
• Evidence: experimental ; cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PCR-based expression analysis and identification of microRNAs
   "Lu DP, Read RL, Humphreys DT, Battah FM, Martin DIK, Rasko JEJ"
   "RNAi and Gene Silencing (2005) 1:44-49