Stem-loop dre-mir-212-1

Accession

MI0003385

Description

Danio rerio dre-mir-212-1 precursor miRNA

Literature search

34 open access papers mention dre-mir-212-1
(307 sentences)

Sequence

265955 reads, 186.0 reads per million, 260 experiments

gucagugcaucaauACCUUGGCUCUAGACUGCUUACUGcuaaaugugucugaaaguacagUAACAGUCUACAGUCAUGGCUACugacgucuggc
(((((.((.(((.((((.(((((.(((((((.((((((...................))))))))))))).))))).)).)).))).)))))))

Structure

     u  a   a  -  U     C       C      cuaaaugu 
gucag gc uca uA CC UGGCU UAGACUG UUACUG        g
||||| || ||| || || ||||| ||||||| ||||||        u
cgguc ug agu AU GG ACUGA AUCUGAC AAUgac        c
     -  c   C  C  U     C       -      augaaagu 

Annotation confidence High

Comments

This miRNA was predicted by computational methods using conservation between human, mouse and Fugu rubripes sequences [1]. Expression of the excised miR was validated in zebrafish, and the 5' end mapped by PCR. The 3' end was not experimentally determined.

Genome context

chr15: 25897446-25897539 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from dre-mir-212-1

Mature dre-miR-212-5p

• Accession: MIMAT0048650
• Description: Danio rerio dre-miR-212-5p mature miRNA
• Sequence: 15 - ACCUUGGCUCUAGACUGCUUACUG - 38
• Evidence: experimental

Mature dre-miR-212-3p

• Accession: MIMAT0048651
• Description: Danio rerio dre-miR-212-3p mature miRNA
• Sequence: 61 - UAACAGUCUACAGUCAUGGCUAC - 83
• Evidence: experimental

References

1. PubMed ID: 12624257
   Vertebrate microRNA genes
   "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
   "Science (2003) 299:1540