Stem-loop mmu-mir-486a

Accession

MI0003493

Description

Mus musculus mmu-mir-486a precursor miRNA mir-486

Gene
family

RF00784; mir-486

Literature search

70 open access papers mention mmu-mir-486a
(605 sentences)

Sequence

1785599 reads, 2476 reads per million, 102 experiments

cagccagcucugaucucgcccucccugaggggUCCUGUACUGAGCUGCCCCGAGguccuucacugugcucagcuCGGGGCAGCUCAGUACAGGAUgcgucagggugggagacaacggggaacaagcca
..((...(((((...((.(((.((((((.(.(((((((((((((((((((((((........(((....)))))))))))))))))))))))))).).)))))).))).))...))))).....))..

Structure

ca  --cag     auc  g   u      g g                       guccuuca   u 
  gc     cucug   uc ccc cccuga g gUCCUGUACUGAGCUGCCCCGAG        cug g
  ||     |||||   || ||| |||||| | |||||||||||||||||||||||        |||  
  cg     ggggc   ag ggg gggacu c UAGGACAUGACUCGACGGGGCuc        gac c
ac  aacaa     aac  a   u      g g                       --------   u 

Annotation confidence High

Genome context

chr8: 23142555-23142682 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-486a

Mature mmu-miR-486a-5p

• Accession: MIMAT0003130
• Description: Mus musculus mmu-miR-486a-5p mature miRNA
• Sequence: 33 - UCCUGUACUGAGCUGCCCCGAG - 54
• Evidence: experimental ; cloned [1], Illumina [2-3]

Mature mmu-miR-486a-3p

• Accession: MIMAT0017206
• Description: Mus musculus mmu-miR-486a-3p mature miRNA
• Sequence: 75 - CGGGGCAGCUCAGUACAGGAU - 95
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009