miRBase entry: hsa-mir-455

Stem-loop hsa-mir-455


Accession
MI0003513
Symbol
HGNC: MIR455
Description
Homo sapiens hsa-mir-455 precursor miRNA mir-455
Gene
family?
RF00709; mir-455

Literature search
75 open access papers mention hsa-mir-455
(620 sentences)

Sequence

49975 reads, 927 reads per million, 127 experiments
ucccuggcgugagggUAUGUGCCUUUGGACUACAUCGuggaagccagcaccauGCAGUCCAUGGGCAUAUACACuugccucaaggccuaugucauc
.....(((.(((((((((((((((.((((((.(((.(((........))).))).)))))).)))))))))).....)))))..))).........

Structure
----ucccu   -g     -----          U      A   C   gaa 
         ggc  ugagg     gUAUGUGCCU UGGACU CAU Gug   g
         |||  |||||     |||||||||| |||||| ||| |||    
         ccg  acucc     CAUAUACGGG ACCUGA Gua cac   c
cuacuguau   ga     guuCA          U      C   c   gac 


Annotation confidence Not enough data
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Comments
The mir-455 precursor was predicted computationally and a 5' mature product verified in human by Northern blot [1]. The precise sequence termini of the mature forms were derived by cloning from human and rat samples [2].

Genome context
chr9: 114209434-114209529 [+]

Disease association
hsa-mir-455 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-455-5p

Accession MIMAT0003150
Description Homo sapiens hsa-miR-455-5p mature miRNA
Sequence 16 - UAUGUGCCUUUGGACUACAUCG - 37
Evidence experimental
Northern [1], cloned [2-3]
Database links
Predicted targets

Mature hsa-miR-455-3p

Accession MIMAT0004784
Description Homo sapiens hsa-miR-455-3p mature miRNA
Sequence 54 - GCAGUCCAUGGGCAUAUACAC - 74
Evidence experimental
cloned [2-3]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  3. PubMed ID: 15652478
    Phylogenetic shadowing and computational identification of human microRNA genes
    "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
    "Cell (2005) 120:21-24