Stem-loop hsa-mir-92b

Accession

MI0003560

Symbol

HGNC: MIR92B

Description

Homo sapiens hsa-mir-92b precursor miRNA

Literature search

201 open access papers mention hsa-mir-92b
(623 sentences)

Sequence

93988 reads, 954 reads per million, 128 experiments

cgggccccgggcgggcgggAGGGACGGGACGCGGUGCAGUGuuguuuuuucccccgccaaUAUUGCACUCGUCCCGGCCUCCggcccccccggccc
.(((((..(((.((((.(((((..(((((((.((((((((((((.............))))))))))))))))))).))))).))))))).)))))

Structure

c     cc   c    g     GA       C            uuuuu 
 gggcc  ggg gggc ggAGG  CGGGACG GGUGCAGUGuug     u
 |||||  ||| |||| |||||  ||||||| ||||||||||||     c
 cccgg  ccc cccg CCUCC  GCCCUGC UCACGUUAUaac     c
-     -c   -    g     -G       -            cgccc 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr1: 155195177-155195272 [+]

Disease association

hsa-mir-92b is associated with one or more human diseases in the Human microRNA Disease Database

Biological pathways

hsa-mir-92b is involved in one or more biological pathways:

(Source: Reactome)

Biological reactions

hsa-mir-92b is involved in one or more regulation/signalling events:

(Source: Reactome)

Mature hsa-miR-92b-5p

• Accession: MIMAT0004792
• Description: Homo sapiens hsa-miR-92b-5p mature miRNA
• Sequence: 20 - AGGGACGGGACGCGGUGCAGUG - 41
• Evidence: experimental ; cloned [2]

Mature hsa-miR-92b-3p

• Accession: MIMAT0003218
• Description: Homo sapiens hsa-miR-92b-3p mature miRNA
• Sequence: 61 - UAUUGCACUCGUCCCGGCCUCC - 82
• Evidence: experimental ; Microarray [1], RT-PCR [1], SAGE [1], cloned [2-3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


3. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692