miRBase entry: hsa-mir-548c

Stem-loop hsa-mir-548c

Accession

MI0003630

Symbol

HGNC: MIR548C

Description

Homo sapiens hsa-mir-548c precursor miRNA

Literature search

58 open access papers mention hsa-mir-548c
(257 sentences)

Sequence

2341 reads, 142 reads per million, 85 experiments

cauuggcaucuauuagguuggugcAAAAGUAAUUGCGGUUUUUGCCauuacuuucaguagCAAAAAUCUCAAUUACUUUUGCaccaacuuaauacuu
..........(((((((((((((((((((((((((.(((((((((...((((...))))))))))))).)))))))))))))))))))))))))...

Structure

cauuggcauc                         C         Cau    u 
          uauuagguuggugcAAAAGUAAUUG GGUUUUUGC   uacu  
          ||||||||||||||||||||||||| |||||||||   |||| u
          auaauucaaccaCGUUUUCAUUAAC CUAAAAACg   auga  
-------uuc                         U         ---    c

Annotation confidence Not enough data

Do you think this miRNA is real?

Comments

Extensive cloning studies suggest that the 5' miRNA may be the predominant one [2].

Genome context

chr12: 64622509-64622605 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-548c

Name	Accession	Chromosome	Start	End	Strand	Confidence

Disease association

hsa-mir-548c is associated with one or more human diseases in the Human microRNA Disease Database

Disease	Description	Category	PubMed ID

Database links

Mature hsa-miR-548c-5p

Accession	MIMAT0004806
Description	Homo sapiens hsa-miR-548c-5p mature miRNA
Sequence	25 - AAAAGUAAUUGCGGUUUUUGCC - 46
Evidence	experimental cloned [2]
Database links
Predicted targets

Mature hsa-miR-548c-3p

Accession	MIMAT0003285
Description	Homo sapiens hsa-miR-548c-3p mature miRNA
Sequence	61 - CAAAAAUCUCAAUUACUUUUGC - 82
Evidence	experimental SAGE [1]

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414

PubMed ID: 16505370
The colorectal microRNAome
"Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
"Proc Natl Acad Sci U S A (2006) 103:3687-3692