Stem-loop hsa-mir-636

Accession

MI0003651

Symbol

HGNC: MIR636

Description

Homo sapiens hsa-mir-636 precursor miRNA

Literature search

36 open access papers mention hsa-mir-636
(106 sentences)

Sequence

5944 reads, 55.0 reads per million, 136 experiments

uggcggccugggcgggagcgcgcGGGCGGGGCCGGCCCCGCugccuggaauuaaccccgcUGUGCUUGCUCGUCCCGCCCGCAgcccuaggcggcgucg
..((.(((((((.....((..(((((((((((.(((..(((.((..((......))..)).)))...))).))))))))))).))))))))).))....

Structure

--ug  g       cggga  gc           C   -CC   u  cu  aa 
    gc gccuggg     gc  gcGGGCGGGGC GGC   CGC gc  gg  u
    || |||||||     ||  ||||||||||| |||   ||| ||  ||   
    cg cggaucc     cg  CGCCCGCCCUG UCG   GUG cg  cc  u
gcug  g       -----  -A           C   UUC   U  cc  aa 

Annotation confidence Medium

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context

chr17: 76736450-76736548 [-]

Disease association

hsa-mir-636 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-636-5p

• Accession: MIMAT0050509
• Description: Homo sapiens hsa-miR-636-5p mature miRNA
• Sequence: 24 - GGGCGGGGCCGGCCCCGC - 41
• Evidence: experimental ; SAGE [1], cloned [2]

Mature hsa-miR-636-3p

• Accession: MIMAT0003306
• Description: Homo sapiens hsa-miR-636-3p mature miRNA
• Sequence: 61 - UGUGCUUGCUCGUCCCGCCCGCA - 83
• Evidence: experimental ; SAGE [1], cloned [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16505370
   The colorectal microRNAome
   "Cummins JM, He Y, Leary RJ, Pagliarini R, Diaz LA Jr, Sjoblom T, Barad O, Bentwich Z, Szafranska AE, Labourier E, Raymond CK, Roberts BS, Juhl H, Kinzler KW, Vogelstein B, Velculescu VE"
   "Proc Natl Acad Sci U S A (2006) 103:3687-3692