Stem-loop hsa-mir-670

Accession

MI0003933

Symbol

HGNC: MIR670

Description

Homo sapiens hsa-mir-670 precursor miRNA

Literature search

6 open access papers mention hsa-mir-670
(7 sentences)

Sequence

121 reads, 5.0 reads per million, 16 experiments

guuuagggguggaccugauGUCCCUGAGUGUAUGUGGUGAACCugaauuugccuugggUUUCCUCAUAUUCAUUCAGGAGUgucaguugccccuucac
((..((((((((..((((((.(((((((((.((((((.((((((((.......)))))))).).))))).)))))))).)))))))))))))))..))

Structure

  uu        ac      U -        U     - U        au 
gu  aggggugg  cugauG C CCUGAGUG AUGUG G GAACCuga  u
||  ||||||||  |||||| | |||||||| ||||| | ||||||||  u
ca  uccccguu  gacugU G GGACUUAC UAUAC C UUUggguu  g
  cu        --      - A        U     U C        cc 

Annotation confidence High

Comments

Berezikov et al. proposed this sequence as a miRNA candidate based on the RAKE method [1]. Artzi et al. later showed that it is a homolog of a validated miRNA in mouse [2].

Genome context

chr11: 43559656-43559753 [+]

Disease association

hsa-mir-670 is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-670-5p

• Accession: MIMAT0010357
• Description: Homo sapiens hsa-miR-670-5p mature miRNA
• Sequence: 20 - GUCCCUGAGUGUAUGUGGUGAACC - 43
• Evidence: experimental ; RAKE [1], Illumina [3]

Mature hsa-miR-670-3p

• Accession: MIMAT0026640
• Description: Homo sapiens hsa-miR-670-3p mature miRNA
• Sequence: 59 - UUUCCUCAUAUUCAUUCAGGAGU - 81
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298


2. PubMed ID: 18215311
   miRNAminer: a tool for homologous microRNA gene search
   "Artzi S, Kiezun A, Shomron N"
   "BMC Bioinformatics (2008) 9:39


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45