miRBase entry: mmu-mir-1224

Stem-loop mmu-mir-1224


Accession
MI0004118
Symbol
MGI: Mir1224
Description
Mus musculus mmu-mir-1224 precursor miRNA mir-1224
Gene
family?
RF00942; mir-1224

Literature search
22 open access papers mention mmu-mir-1224
(57 sentences)

Sequence

22226 reads, 112 reads per million, 41 experiments
GUGAGGACUGGGGAGGUGGAGgguagcaucauuagagccagagcucugucucagcucccucuccCCCCACCUCUUCUCUCCUCAG
.((((((..((((((((((((((.(((.....((((((....)))))).....)))))))......))))))))))..)))))).

Structure
G      CU          ------    u   aucau      c 
 UGAGGA  GGGGAGGUGG      AGgg agc     uagagc a
 ||||||  ||||||||||      |||| |||     ||||||  
 ACUCCU  CUUCUCCACC      uccc ucg     gucucg g
G      CU          CCccuc    -   acucu      a 


Annotation confidence Not enough data
Do you think this miRNA is real?
Comments
This sequence was identified as a miRNA candidate by Berezikov et al [1], and confirmed later by more extensive cloning [2].

Genome context
chr16: 20604452-20604536 [+]

Database links

Mature mmu-miR-1224-5p

Accession MIMAT0005460
Description Mus musculus mmu-miR-1224-5p mature miRNA
Sequence 1 - GUGAGGACUGGGGAGGUGGAG - 21
Evidence experimental
RAKE [1], cloned [2], Illumina [3-4]
Database links
Predicted targets

Mature mmu-miR-1224-3p

Accession MIMAT0017231
Description Mus musculus mmu-miR-1224-3p mature miRNA
Sequence 65 - CCCCACCUCUUCUCUCCUCAG - 85
Evidence experimental
Illumina [4]

References

  1. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  2. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  3. PubMed ID: 16954537
    Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
    "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
    "Genome Res (2006) 16:1289-1298

  4. PubMed ID: 17964270
    Mammalian mirtron genes
    "Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC"
    "Mol Cell (2007) 28:328-336