Stem-loop mmu-mir-1224

Accession

MI0004118

Symbol

MGI: Mir1224

Description

Mus musculus mmu-mir-1224 precursor miRNA mir-1224

Gene
family

RF00942; mir-1224

Literature search

22 open access papers mention mmu-mir-1224
(57 sentences)

Sequence

22225 reads, 41 reads per million, 41 experiments

GUGAGGACUGGGGAGGUGGAGgguagcaucauuagagccagagcucugucucagcucccucuccCCCCACCUCUUCUCUCCUCAG
.((((((..((((((((((((((.(((.....((((((....)))))).....)))))))......))))))))))..)))))).

Structure

G      CU          ------    u   aucau      c 
 UGAGGA  GGGGAGGUGG      AGgg agc     uagagc a
 ||||||  ||||||||||      |||| |||     ||||||  
 ACUCCU  CUUCUCCACC      uccc ucg     gucucg g
G      CU          CCccuc    -   acucu      a 

Annotation confidence Not enough data

Comments

This sequence was identified as a miRNA candidate by Berezikov et al [1], and confirmed later by more extensive cloning [2].

Genome context

chr16: 20604452-20604536 [+]

Mature mmu-miR-1224-5p

• Accession: MIMAT0005460
• Description: Mus musculus mmu-miR-1224-5p mature miRNA
• Sequence: 1 - GUGAGGACUGGGGAGGUGGAG - 21
• Evidence: experimental ; RAKE [1], cloned [2], Illumina [3-4]

Mature mmu-miR-1224-3p

• Accession: MIMAT0017231
• Description: Mus musculus mmu-miR-1224-3p mature miRNA
• Sequence: 65 - CCCCACCUCUUCUCUCCUCAG - 85
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


2. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


3. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298


4. PubMed ID: 17964270
   Mammalian mirtron genes
   "Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC"
   "Mol Cell (2007) 28:328-336