Accession
MI0004733
Description
Bos taurus
bta-mir-29a precursor miRNA
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
WARNING: This summary was generated by AI. bta-mir-29a, a microRNA, is notably expressed at higher levels in the adult bovine ovarian cortex compared to the fetal ovary, indicating a potential role in ovarian function and development [PMC2762473]. This microRNA was chosen for cellular localization studies due to its differential expression, suggesting its significance in reproductive tissues [PMC2762473]. Additionally, bta-mir-29a is among the miRNAs differentially expressed in bovine milk and plasma during early pregnancy [PMC6418173], and it has been implicated in processes related to pregnancy maintenance and immune function [PMC9445238]. Its stability has led to its proposed use as an internal control for normalizing qPCR data in studies involving bovine milk small extracellular vesicles (sEVs) [PMC9961204]. Network analysis further associates bta-mir-29a with key uterine proteins, indicating a strong interaction with reproductive processes at the molecular level [PMC8273763]. Despite variable expression patterns observed under different conditions, bta-mir-29a's consistent association with reproductive tissues underscores its potential as a biomarker for reproductive status and health in cattle [PMC5662615], while also being inversely correlated with lysosomal activity suggesting an involvement in cellular processes beyond reproduction [PMC9378797].
Literature search
224 open access papers mention bta-mir-29a
(1153 sentences)
(1153 sentences)
Sequence
6129782
reads,
2334.0
reads per million, 321 experiments
augACUGAUUUCUUUUGGUGUUCAGagucaauauaauuuuCUAGCACCAUCUGAAAUCGGUUAU
((((((((((((...(((((((.((((...........)))))))))))...))))))))))))
((((((((((((...(((((((.((((...........)))))))))))...))))))))))))
Structure
UUU C ucaa
augACUGAUUUC UGGUGUU AGag u
|||||||||||| ||||||| |||| a
UAUUGGCUAAAG ACCACGA UCuu u
UCU - uuaa
Annotation confidence
High
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Genome context
4: 94636467-94636530 [-]
Clustered miRNAs
1 other miRNA is < 10 kb from bta-mir-29a
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature bta-miR-29a-5p
| Accession | MIMAT0060928 |
| Description | Bos taurus bta-miR-29a-5p mature miRNA |
| Sequence | 4 - ACUGAUUUCUUUUGGUGUUCAG - 25 |
| Evidence |
experimental
cloned [1-2] |
Mature bta-miR-29a-3p
| Accession | MIMAT0003518 |
| Description | Bos taurus bta-miR-29a-3p mature miRNA |
| Sequence | 41 - CUAGCACCAUCUGAAAUCGGUUAU - 64 |
| Evidence |
experimental
cloned [1-2] |
References
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