miRBase entry: ebv-mir-BART20

Stem-loop ebv-mir-BART20

Accession

MI0004993

Description

Epstein Barr virus ebv-mir-BART20 precursor miRNA

Sequence

uacaggcguagggccuauugUAGCAGGCAUGUCUUCAUUCCugcguaccgaauggCAUGAAGGCACAGCCUGUUACCauuggcaccuuuuuuccaugua
((((((...((((((.((.(((((((((.(((((((((.((............)).)))))))))..))))))))).)).))).))).....)).))))

Structure

    -  --cgu   -   u  u         -A         U  ugcgu 
uaca gg     agg gcc au gUAGCAGGC  UGUCUUCAU CC     a
|||| ||     ||| ||| || |||||||||  ||||||||| ||      
augu cc     ucc cgg ua CAUUGUCCG  ACGGAAGUA gg     c
    a  uuuuu   a   u  C         AC         C  uaagc

Annotation confidence Not enough data

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Comments

The arm of the precursor miRNA giving rise to the mature sequence was verified using microarray hybridisation and Northern blot, but the extents of the mature miRNA shown here are predicted and not experimentally determined [1]. This sequence was named miR-BART18 by Grundhoff et al [1]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

HHV507799: 148319-148417 [+]

Clustered miRNAs

21 other miRNAs are < 10 kb from ebv-mir-BART20

Name	Accession	Chromosome	Start	End	Strand	Confidence

Database links

Mature ebv-miR-BART20-5p

Accession	MIMAT0003719
Description	Epstein Barr virus ebv-miR-BART20-5p mature miRNA
Sequence	21 - UAGCAGGCAUGUCUUCAUUCC - 41
Evidence	experimental array [1], Northern [1], cloned [2]

Mature ebv-miR-BART20-3p

Accession	MIMAT0003720
Description	Epstein Barr virus ebv-miR-BART20-3p mature miRNA
Sequence	56 - CAUGAAGGCACAGCCUGUUACC - 77
Evidence	experimental array [1], Northern [1], cloned [2]

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414

PubMed ID: 16540699
A combined computational and microarray-based approach identifies novel microRNAs encoded by human gamma-herpesviruses
"Grundhoff A, Sullivan CS, Ganem D"
"RNA (2006) 12:733-750