Stem-loop bta-let-7i

Accession

MI0005065

Description

Bos taurus bta-let-7i precursor miRNA

Literature search

53 open access papers mention bta-let-7i
(253 sentences)

Sequence

614624 reads, 3806 reads per million, 76 experiments

cuggcUGAGGUAGUAGUUUGUGCUGUUggucggguugugacauugcccgcuguggagauaacugcgcaagcuacugccuugcua
.((((.(((((((((((((((((.(((((.(((((.........)))))))........))).)))))))))))))))))))))

Structure

c    U                 U   --------  u     ugu 
 uggc GAGGUAGUAGUUUGUGC GUU        gg cgggu   g
 |||| ||||||||||||||||| |||        || |||||   a
 aucg uuccgucaucgaacgcg caa        uc gcccg   c
-    -                 u   uagaggug  -     uua 

Annotation confidence High

Comments

The 5' terminal base of the mature let-7i sequence identified by Coutinho et al [1] is reported as C, which conflicts with the draft genome sequence that requires U as shown here. The 5' end reported by Gu et al. is shorter by 7 nts [2].

Genome context

chr5: 51387456-51387539 [-]

Mature bta-let-7i

• Accession: MIMAT0003851
• Description: Bos taurus bta-let-7i mature miRNA
• Sequence: 6 - UGAGGUAGUAGUUUGUGCUGUU - 27
• Evidence: experimental ; cloned [1-3]

References

1. PubMed ID: 17105755
   Discovery and profiling of bovine microRNAs from immune-related and embryonic tissues
   "Coutinho LL, Matukumalli LK, Sonstegard TS, Van Tassell CP, Gasbarre LC, Capuco AV, Smith TP"
   "Physiol Genomics (2007) 29:35-43


2. PubMed ID: 17306260
   Identification and characterization of microRNAs from the bovine adipose tissue and mammary gland
   "Gu Z, Eleswarapu S, Jiang H"
   "FEBS Lett (2007) 581:981-988


3. PubMed ID: 19267191
   Identification and characteristics of cattle microRNAs by homology searching and small RNA cloning
   "Long JE, Chen HX"
   "Biochem Genet (2009) 47:329-343