Stem-loop mmu-mir-466f-2

Accession

MI0005508

Symbol

MGI: Mir466f-2

Description

Mus musculus mmu-mir-466f-2 precursor miRNA

Literature search

28 open access papers mention mmu-mir-466f-2
(68 sentences)

Sequence

7407 reads, 39.0 reads per million, 146 experiments

aauguguguuuacgugUGUGUGCAUGUGCAUGUGUGUAUaugaauauauguauacAUACACACACACAUACACACUCauguaacacacacacac
..((((((((((((((.(((((.(((((..(((((((((((........)))))))))))....))))).))))).))))))).)))))))...

Structure

-aa       -       U     C     --CA           gaa 
   ugugugu uuacgug GUGUG AUGUG    UGUGUGUAUau   u
   ||||||| ||||||| ||||| |||||    |||||||||||    
   acacaca aauguaC CACAC UACAC    ACAUAcauaug   a
cac       c       U     A     ACAC           uau 

Annotation confidence Medium

Comments

Landgraf et al. identify several offset sequences which map to the 3' arm of the miR-466f hairpin precursors [1]. One sequence consistent with all three putative hairpin loci is shown here.

Genome context

chr2: 10468675-10468768 [+]

Clustered miRNAs

6 other miRNAs are < 10 kb from mmu-mir-466f-2

Mature mmu-miR-466f-5p

• Accession: MIMAT0004881
• Description: Mus musculus mmu-miR-466f-5p mature miRNA
• Sequence: 17 - UGUGUGCAUGUGCAUGUGUGUAU - 39
• Evidence: experimental ; cloned [1], Illumina [2]

Mature mmu-miR-466f-3p

• Accession: MIMAT0004882
• Description: Mus musculus mmu-miR-466f-3p mature miRNA
• Sequence: 56 - AUACACACACACAUACACACUC - 77
• Evidence: experimental ; cloned [1], Illumina [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009