miRBase entry: hsa-mir-541

Stem-loop hsa-mir-541

Accession

MI0005539

Symbol

HGNC: MIR541

Description

Homo sapiens hsa-mir-541 precursor miRNA mir-541

Gene
family?

RF00777; mir-541

Literature search

12 open access papers mention hsa-mir-541
(79 sentences)

Sequence

241 reads, 2 reads per million, 25 experiments

acgucagggAAAGGAUUCUGCUGUCGGUCCCACUccaaaguucacagaaugggUGGUGGGCACAGAAUCUGGACUcugcuugug
(((.(((((...((((((((.((((.(..((((((....((((...))))))))))).))))))))))))...)))))..))).

Structure

-   -u     AAA        C    G UC      caaa    a 
 acg  caggg   GGAUUCUG UGUC G  CCACUc    guuc  
 |||  |||||   |||||||| |||| |  ||||||    |||| c
 ugu  gucUC   UCUAAGAC ACGG U  GGUggg    uaag  
g   uc     AGG        -    G --      ----    a

Annotation confidence High

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Genome context

chr14: 101064495-101064578 [+]

Clustered miRNAs

12 other miRNAs are < 10 kb from hsa-mir-541

Name	Accession	Chromosome	Start	End	Strand	Confidence

Disease association

hsa-mir-541 is associated with one or more human diseases in the Human microRNA Disease Database

Disease	Description	Category	PubMed ID

Database links

Mature hsa-miR-541-5p

Accession	MIMAT0004919
Description	Homo sapiens hsa-miR-541-5p mature miRNA
Sequence	10 - AAAGGAUUCUGCUGUCGGUCCCACU - 34
Evidence	not_experimental
Database links
Predicted targets

Mature hsa-miR-541-3p

Accession	MIMAT0004920
Description	Homo sapiens hsa-miR-541-3p mature miRNA
Sequence	54 - UGGUGGGCACAGAAUCUGGACU - 75
Evidence	experimental cloned [1]

References

PubMed ID: 17604727
A mammalian microRNA expression atlas based on small RNA library sequencing
"Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
"Cell (2007) 129:1401-1414