Stem-loop mmu-mir-875

Accession

MI0005551

Symbol

MGI: Mir875

Description

Mus musculus mmu-mir-875 precursor miRNA mir-875

Gene
family

RF00933; mir-875

Literature search

15 open access papers mention mmu-mir-875
(20 sentences)

Sequence

268 reads, 7.0 reads per million, 24 experiments

ucugugguacUAUACCUCAGUUUUAUCAGGUGUucauuaaaaucaCCUGAAAAUACUGAGGCUAUGUUucacugagca
((.((((.((.((((((((((.((.(((((((...........))))))).)).))))))).))))).)))).))...

Structure

---  u    u  U   -       U  A       Uuca 
   uc gugg ac AUA CCUCAGU UU UCAGGUG    u
   || |||| || ||| ||||||| || |||||||    u
   ag cacu UG UAU GGAGUCA AA AGUCCac    a
acg  u    U  -   C       U  A       uaaa 

Annotation confidence High

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was independently shown in human and rat [2].

Genome context

15: 35661116-35661193 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-875

Mature mmu-miR-875-5p

• Accession: MIMAT0004937
• Description: Mus musculus mmu-miR-875-5p mature miRNA
• Sequence: 11 - UAUACCUCAGUUUUAUCAGGUGU - 33
• Evidence: experimental ; RAKE [1], Illumina [3]

Mature mmu-miR-875-3p

• Accession: MIMAT0004938
• Description: Mus musculus mmu-miR-875-3p mature miRNA
• Sequence: 46 - CCUGAAAAUACUGAGGCUAUGUU - 68
• Evidence: experimental ; RAKE [1], Illumina [3]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


3. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298