Stem-loop ame-mir-137

Accession

MI0005729

Description

Apis mellifera ame-mir-137 precursor miRNA mir-137

Gene
family

RF00694; mir-137

Literature search

3 open access papers mention ame-mir-137
(6 sentences)

Sequence

22035 reads, 282.0 reads per million, 24 experiments

gacuucauaggccagguuggcgACGCGUAUUCUUGGGGAAUUAACAcacauuugcgcugUUAUUGCUUGAGAAUACACGUAGuuugccuggucguucacu
.........((((((((.(((.(((.(((((((((((.(((.(((((.(....).).))))))).))))))))))).))).))).)))))))).......

Structure

gacuucaua        u   g   C           G   U    - a a 
         ggccaggu ggc ACG GUAUUCUUGGG AAU AACA c c u
         |||||||| ||| ||| ||||||||||| ||| |||| | |  
         cugguccg uuG UGC CAUAAGAGUUC UUA UUgu g g u
--ucacuug        u   A   A           G   -    c c u 

Annotation confidence High

Comments

Weaver et al. identify a second variant mature miRNA sequence offset including an extra 2 nt (UG) at the 5' end, and 3 nt at the 3' end (GUU) [1]

Genome context

CM000065.5: 5447771-5447870 [-]

Mature ame-miR-137-5p

• Accession: MIMAT0053061
• Description: Apis mellifera ame-miR-137-5p mature miRNA
• Sequence: 23 - ACGCGUAUUCUUGGGGAAUUAACA - 46
• Evidence: experimental ; RTPCR [1], Illumina [2-3]

Mature ame-miR-137-3p

• Accession: MIMAT0004421
• Description: Apis mellifera ame-miR-137-3p mature miRNA
• Sequence: 60 - UUAUUGCUUGAGAAUACACGUAG - 82
• Evidence: experimental ; RTPCR [1], Illumina [2-3]

References

1. PubMed ID: 17543122
   Computational and transcriptional evidence for microRNAs in the honey bee genome
   Weaver DB, Anzola JM, Evans JD, Reid JG, Reese JT, Childs KL, Zdobnov EM, Samanta MP, Miller J, Elsik CG
   Genome Biol (2007) 8:R97


2. PubMed ID: 22409512
   Behavioral plasticity in honey bees is associated with differences in brain microRNA transcriptome
   "Greenberg JK, Xia J, Zhou X, Thatcher SR, Gu X, Ament SA, Newman TC, Green PJ, Zhang W, Robinson GE, Ben-Shahar Y"
   "Genes Brain Behav (2012) 11:660-670


3. PubMed ID: 26853694
   MicroRNA signatures characterizing caste-independent ovarian activity in queen and worker honeybees (Apis mellifera L.)
   "Macedo LM, Nunes FM, Freitas FC, Pires CV, Tanaka ED, Martins JR, Piulachs MD, Cristino AS, Pinheiro DG, Simoes ZL"
   "Insect Mol Biol (2016) 25:216-226