Accession
MI0005767
Symbol
HGNC:
MIR942
Description
Homo sapiens
hsa-mir-942 precursor miRNA mir-942
Gene
family?
family?
RF00997;
mir-942
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR942 is a microRNA molecule that has been studied in various contexts. In blood platelets from patients with NSTEMI, it was found to be one of the most downregulated miRNAs [PMC5155104]. In ovarian cancer, the circular RNA CircEPSTI1 was found to promote cancer progression by inhibiting MIR942 [PMC7479240]. Additionally, upregulation of MIR942 has been associated with sunitinib resistance in patients with metastatic renal cell carcinoma [PMC6917607]. However, there is limited research on MIR942 in the context of ADHD, with only one study found [PMC8077053]. In a different study, two consecutive probes downstream of a top 20 probe for MIR942 reached a significant threshold and were differentially methylated CpGs [PMC9922242]. Furthermore, in two studies based on the GSE94462 dataset, MIR942 was among several microRNAs that were analyzed [PMC9922242]. In another study on obstructive sleep apnea (OSA), the expression of KCNN2 and MIR942 significantly increased as OSA progressed and significantly decreased after treatment [PMC9554663]. Additionally, the expression of KCNN2 and other genes such as PLXNB3 and SERPINA12 were positively correlated with apnea-hypopnea index (AHI) in OSA patients [PMC9554663]. Overall, these studies highlight the potential role of MIR942 in various diseases and conditions.
Literature search
11 open access papers mention hsa-mir-942
(124 sentences)
(124 sentences)
Sequence
2773
reads,
124
reads per million, 78 experiments
auuaggagaguaUCUUCUCUGUUUUGGCCAUGUGuguacucacagccccucaCACAUGGCCGAAACAGAGAAGUuacuuuccuaau
((((((((((((.(((((((((((((((((((((((..............))))))))))))))))))))))).))))))))))))
((((((((((((.(((((((((((((((((((((((..............))))))))))))))))))))))).))))))))))))
Structure
U uacuca
auuaggagagua CUUCUCUGUUUUGGCCAUGUGug c
|||||||||||| |||||||||||||||||||||||
uaauccuuucau GAAGAGACAAAGCCGGUACACac a
U uccccg
Annotation confidence
High
Do you think this miRNA is real?
Genome context
chr1: 117094643-117094728 [+]
Disease association
hsa-mir-942 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-942-5p
| Accession | MIMAT0004985 |
| Description | Homo sapiens hsa-miR-942-5p mature miRNA |
| Sequence | 13 - UCUUCUCUGUUUUGGCCAUGUG - 34 |
| Evidence |
experimental
cloned [1], Illumina [2] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-942-3p
| Accession | MIMAT0026734 |
| Description | Homo sapiens hsa-miR-942-3p mature miRNA |
| Sequence | 53 - CACAUGGCCGAAACAGAGAAGU - 74 |
| Evidence |
experimental
Illumina [2] |
| Database links |
|
| Predicted targets |
|
References
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