miRBase entry: hsa-mir-942

Stem-loop hsa-mir-942

Homo sapiens hsa-mir-942 precursor miRNA
Gene family
MIPF0000511; mir-942

Caution, this is an AI generated summary based on literature. This may have errors. ?

MIR942 is a microRNA molecule that has been studied in various contexts. In blood platelets from patients with NSTEMI, it was found to be one of the most downregulated miRNAs [PMC5155104]. In ovarian cancer, the circular RNA CircEPSTI1 was found to promote cancer progression by inhibiting MIR942 [PMC7479240]. Additionally, upregulation of MIR942 has been associated with sunitinib resistance in patients with metastatic renal cell carcinoma [PMC6917607]. However, there is limited research on MIR942 in the context of ADHD, with only one study found [PMC8077053]. In a different study, two consecutive probes downstream of a top 20 probe for MIR942 reached a significant threshold and were differentially methylated CpGs [PMC9922242]. Furthermore, in two studies based on the GSE94462 dataset, MIR942 was among several microRNAs that were analyzed [PMC9922242]. In another study on obstructive sleep apnea (OSA), the expression of KCNN2 and MIR942 significantly increased as OSA progressed and significantly decreased after treatment [PMC9554663]. Additionally, the expression of KCNN2 and other genes such as PLXNB3 and SERPINA12 were positively correlated with apnea-hypopnea index (AHI) in OSA patients [PMC9554663]. Overall, these studies highlight the potential role of MIR942 in various diseases and conditions.

Literature search
11 open access papers mention hsa-mir-942
(124 sentences)


2773 reads, 124 reads per million, 78 experiments

            U                       uacuca 
auuaggagagua CUUCUCUGUUUUGGCCAUGUGug      c
|||||||||||| |||||||||||||||||||||||       
uaauccuuucau GAAGAGACAAAGCCGGUACACac      a
            U                       uccccg 

Annotation confidence High
Do you think this miRNA is real?

Genome context
chr1: 117094643-117094728 [+]

Disease association
hsa-mir-942 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID

Database links

Mature hsa-miR-942-5p

Accession MIMAT0004985
Description Homo sapiens hsa-miR-942-5p mature miRNA
Evidence experimental
cloned [1], Illumina [2]
Database links
Predicted targets

Mature hsa-miR-942-3p

Accession MIMAT0026734
Description Homo sapiens hsa-miR-942-3p mature miRNA
Evidence experimental
Illumina [2]
Database links
Predicted targets


  1. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  2. PubMed ID: 23034410
    Birth and expression evolution of mammalian microRNA genes
    "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
    "Genome Res (2013) 23:34-45