miRBase entry: hiv1-mir-H1

Stem-loop hiv1-mir-H1


Accession
MI0006106
Description
Human immunodeficiency virus 1 hiv1-mir-H1 precursor miRNA


Sequence

uCCAGGGAGGCGUGCCUGGGCgggacuggggaguggcgcccucagauccugcauauaagcagcgcuuuuuucggugcguua
.((((((((((((((....((((((((((((.((...)))))))).))))))......))).))))))))).)).......

Structure
------u  -         -   --CUGG      -      a  g 
       CC AGGGAGGCG UGC      GCggga cugggg gu  
       || ||||||||| |||      |||||| |||||| || g
       gg uuuuuucgc acg      cguccu gacucc cg  
auugcgu  c         g   aauaua      a      -  c 


Annotation confidence Not enough data
Do you think this miRNA is real?

Genome context
Unknown

Database links

Mature hiv1-miR-H1

Accession MIMAT0004480
Description Human immunodeficiency virus 1 hiv1-miR-H1 mature miRNA
Sequence 2 - CCAGGGAGGCGUGCCUGGGC - 21
Evidence experimental
Northern [1]

References

  1. PubMed ID: 15782219
    Identification of microRNAs of the herpesvirus family
    "Pfeffer S, Sewer A, Lagos-Quintana M, Sheridan R, Sander C, Grasser FA, van Dyk LF, Ho CK, Shuman S, Chien M, Russo JJ, Ju J, Randall G, Lindenbach BD, Rice CM, Simon V, Ho DD, Zavolan M, Tuschl T"
    "Nat Methods (2005) 2:269-276

  2. PubMed ID: 17855543
    Analysis of the interaction of primate retroviruses with the human RNA interference machinery
    "Lin J, Cullen BR"
    "J Virol (2007) 81:12218-12226

  3. Evidence and nature of a novel miRNA encoded by HIV-1
    "Kaul D, Khanna A and Suman"
    "Proc Indian Natn Sci Acad. (2006) 72:91-95

  4. PubMed ID: 19082544
    HIV-1 genome-encoded hiv1-mir-H1 impairs cellular responses to infection
    "Kaul D, Ahlawat A, Gupta SD"
    "Mol Cell Biochem (2009) 323:143-148

  5. PubMed ID: 20546828
    HIV-miR-H1 evolvability during HIV pathogenesis
    "Lamers SL, Fogel GB, McGrath MS"
    "Biosystems (2010) 101:88-96