Stem-loop rno-mir-652

Accession

MI0006169

Description

Rattus norvegicus rno-mir-652 precursor miRNA

Literature search

7 open access papers mention rno-mir-652
(9 sentences)

Sequence

34416 reads, 36 reads per million, 491 experiments

augcacugcACAACCCUAGGAGGGGGUGCCAUucacauagacuauaauugAAUGGCGCCACUAGGGUUGUGcaguguacaa
.((((((((((((((((((.....(((((((((((..((.....))..))))))))))).))))))))))))))))))...

Structure

--a                  GAGGG           ca  g 
   ugcacugcACAACCCUAG     GGUGCCAUuca  ua a
   ||||||||||||||||||     |||||||||||  || c
   augugacGUGUUGGGAUC     CCGCGGUAAgu  au u
aac                  ----A           ua  a 

Annotation confidence High

Comments

The predominant miRNA cloned by Landgraf et al. has a 3' additional U residue, which is incompatible with the genome sequence [1].

Genome context

chrX: 114002534-114002614 [+]

Mature rno-miR-652-5p

• Accession: MIMAT0017321
• Description: Rattus norvegicus rno-miR-652-5p mature miRNA
• Sequence: 10 - ACAACCCUAGGAGGGGGUGCCAU - 32
• Evidence: experimental ; SOLiD [2]

Mature rno-miR-652-3p

• Accession: MIMAT0005342
• Description: Rattus norvegicus rno-miR-652-3p mature miRNA
• Sequence: 51 - AAUGGCGCCACUAGGGUUGUG - 71
• Evidence: experimental ; cloned [1], SOLiD [2]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249