Stem-loop mcmv-mir-m108-2

Accession

MI0006263

Description

Mouse cytomegalovirus mcmv-mir-m108-2 precursor miRNA

Sequence

gaUCACUCGUCGCGAGCGGUCACUCGACGCGAGCACCGagucgcuacggacgGUGACUCGAGACGAGUGACCGGUcgacgagcguc
((.(.((((((..((.((((((((((.(.((((((((..(((......))))))).)))).).)))))))))).)))))))).)))

Structure

  U A      GC  G          A G    -    Ga   gc 
ga C CUCGUC  GA CGGUCACUCG C CGAG CACC  guc  u
|| | ||||||  || |||||||||| | |||| ||||  |||   
cu g gagcag  cU GCCAGUGAGC G GCUC GUGg  cag  a
  - c      --  G          A A    A    --   gc 

Annotation confidence Not enough data

Comments

Buck et al [1] and Dolken et al [2] cloned alternative offset mature miRNA sequences from the 5' arm of this hairpin precursor, named mir-m108-2-5p.1 and .2 here.

Genome context

Unknown

Mature mcmv-miR-m108-2-5p.2

• Accession: MIMAT0005559
• Description: Mouse cytomegalovirus mcmv-miR-m108-2-5p.2 mature miRNA
• Sequence: 3 - UCACUCGUCGCGAGCGGUCAC - 23
• Evidence: experimental ; cloned [1]

Mature mcmv-miR-m108-2-5p.1

• Accession: MIMAT0005560
• Description: Mouse cytomegalovirus mcmv-miR-m108-2-5p.1 mature miRNA
• Sequence: 16 - GCGGUCACUCGACGCGAGCACCG - 38
• Evidence: experimental ; cloned [2]

Mature mcmv-miR-m108-2-3p

• Accession: MIMAT0005561
• Description: Mouse cytomegalovirus mcmv-miR-m108-2-3p mature miRNA
• Sequence: 53 - GUGACUCGAGACGAGUGACCGGU - 75
• Evidence: experimental ; cloned [1-2]

References

1. PubMed ID: 17942535
   Mouse cytomegalovirus microRNAs dominate the cellular small RNA profile during lytic infection and show features of posttranscriptional regulation
   "Dolken L, Perot J, Cognat V, Alioua A, John M, Soutschek J, Ruzsics Z, Koszinowski U, Voinnet O, Pfeffer S"
   "J Virol (2007) 81:13771-13782


2. PubMed ID: 17928340
   Discrete clusters of virus-encoded micrornas are associated with complementary strands of the genome and the 7.2-kilobase stable intron in murine cytomegalovirus
   "Buck AH, Santoyo-Lopez J, Robertson KA, Kumar DS, Reczko M, Ghazal P"
   "J Virol (2007) 81:13761-13770