Dead hairpin entry

Stem-loop hsa-mir-1291

Accession

MI0006353

Symbol

HGNC: MIR1291

Description

Homo sapiens hsa-mir-1291 precursor miRNA

Comment

The read data does not support this entry being a bona fide miRNA.

Summary

Caution, this is an AI generated summary based on literature. This may have errors.

WARNING: This summary was generated by AI. MIR1291 is a microRNA that has been implicated in various cellular processes and diseases. It has been identified as a regulator of the Rho GTPase activating protein 29 (ArhGAP29) through gene ontology and various database analyses [PMC5647010]. In the context of resistance to tamoxifen in breast cancer cells, MIR1291 is slightly upregulated, suggesting a potential role in the development of resistance [PMC3402532]. Moreover, MIR1291 has been associated with the regulation of glucose transporters GLUT1 and GLUT3 in different cancer cell types, indicating its involvement in metabolic regulation [PMC9663470]. In studies examining exhaled breath condensates, MIR1291 expression was found to be downregulated specifically in asthmatic patients compared to healthy individuals [PMC8196952]. Additionally, after stimulation with IFN-γ, MIR1291 was among the top 10 upregulated microRNAs, highlighting its potential role in immune response modulation [PMC8010072].

Literature search

45 open access papers mention hsa-mir-1291
(289 sentences)

Sequence

6073 reads, 10.0 reads per million, 126 experiments

gguagaauuccaGUGGCCCUGACUGAAGACCAGCAguuguacuguggcuguugguuucaagcagagGCCUAAAGGACUGUCUUCCUG
((.(((..(((...(((((((.((..((((((((((((.......))))))))))))..))))).))))....)))...))).))..

Structure

--  u   -au   -aGU    -   A  GA            gu 
  gg aga   ucc    GGCC CUG CU  AGACCAGCAguu  a
  || |||   |||    |||| ||| ||  ||||||||||||  c
  CC UCU   AGG    CCGg gac ga  uuugguugucgg  u
GU  U   GUC   AAAU    a   -  ac            ug