Accession
MI0006359
Symbol
HGNC:
MIR1299
Description
Homo sapiens
hsa-mir-1299 precursor miRNA mir-1299
Gene
family?
family?
RF04142;
mir-1299
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR1299 is a novel non-coding RNA (ncRNA) marker that has not been previously associated with any diseases, including cancer [PMC5354851]. This study is the first to report the expression of MIR1299 in ameloblastoma tumors [PMC5354851'>PMC5354851]. In addition to MIR1299, other miRNAs such as miR1256, miR205, miR4454, and miR548X were found to be overexpressed in ameloblastoma tumors [PMC5354851]. Furthermore, MIR1299 was found to be upregulated in both ASD and Non-TD subjects, along with other genes such as IGLV1-40, LRRC37A4P, PMCHL2CHL2, TRBV11-2 [PMC6814108]. In Non-TD subjects specifically, LRRC37AP, MIR1299 PMCHL2 and TRBV11-2 were among the top upregulated genes [PMC6814108'>PMC6814108]. Another study demonstrated the overexpression of MIR1299 in ameloblastomas using microarrays and suggested its potential role in the etiopathogenesis of this tumor [PMC7920560]. Additionally, MIR1299 was identified as one of the top genes depleted in a replicate screen along with FAM32A EIF3I BIRC2 BCL2 [PMC9402397]. Finally, based on NGS data from a previous study, MIR1299 was selected as a target for further miRNA analysis [PMC8744551]. References: - PMC5354851 - PMC6814108 - PMC7920560 - PMC9402397 - PMC8744551
Literature search
9 open access papers mention hsa-mir-1299
(19 sentences)
(19 sentences)
Sequence
3343
reads,
43
reads per million, 88 experiments
ccucauggcaguguucuggaauccuacgugagggacaaucauucagacccacguagcagugUUCUGGAAUUCUGUGUGAGGGA
(((((..((((.((((((((((.(((((((.((..............)))))))))....)))))))))).)))).)))))..
(((((..((((.((((((((((.(((((((.((..............)))))))))....)))))))))).)))).)))))..
Structure
-- ug u ---c a gacaau ccuca gcag guucuggaau cuacgug gg c ||||| |||| |||||||||| ||||||| || GGAGU UGUC UAAGGUCUUg gaugcac cc a AG -G U ugac - agacuu
Annotation confidence
Not enough data
Do you think this miRNA is real?
Genome context
chr9: 40929010-40929092 [-]
Disease association
hsa-mir-1299 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-1299
| Accession | MIMAT0005887 |
| Description | Homo sapiens hsa-miR-1299 mature miRNA |
| Sequence | 62 - UUCUGGAAUUCUGUGUGAGGGA - 83 |
| Evidence |
experimental
Illumina [1] |
| Database links |
|
| Predicted targets |
|
References
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