Accession
MI0006381
Symbol
HGNC:
MIR1246
Description
Homo sapiens
hsa-mir-1246 precursor miRNA mir-1246
Gene
family?
family?
RF03434;
mir-1246
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR1246 is a microRNA that has been studied in the context of cancer, where its levels in serum and urine have been analyzed for potential correlations with various aspects of cancer progression [PMC7250935]. Despite the investigation, no significant correlations were found between MIR1246 levels and the extent of tumor invasion, the presence of lymph node metastasis, distant metastasis, or the overall stage of cancer [PMC7250935]. Additionally, MIR1246 has been identified to have a molecular target in cells; it is capable of binding to early B cytokine 1 (EBF1) at its 3′ untranslated region (3′UTR), suggesting a role in post-transcriptional regulation [PMC8258133]. This interaction between MIR1246 and EBF1 indicates that while MIR1246 may not be directly correlated with cancer progression markers such as invasion or metastasis, it could still play a role in cellular processes through its influence on EBF1 [PMC8258133].
Literature search
83 open access papers mention hsa-mir-1246
(525 sentences)
(525 sentences)
Sequence
41973
reads,
1903
reads per million, 98 experiments
uguauccuugAAUGGAUUUUUGGAGCAGGaguggacaccugacccaaaggaaaucaauccauaggcuagcaau
(((..(((...((((((((((((..((((........))))..))))).......))))))))))...)))..
(((..(((...((((((((((((..((((........))))..))))).......))))))))))...)))..
Structure
-- -au ugA ------- AG agu ugu ccu AUGGAUU UUUGG CAGG g ||| ||| ||||||| ||||| |||| acg gga uaccuaa aaacc gucc g ua auc --- cuaaagg ca aca
Annotation confidence
Not enough data
Do you think this miRNA is real?
Genome context
chr2: 176600980-176601052 [-]
Disease association
hsa-mir-1246 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-1246
| Accession | MIMAT0005898 |
| Description | Homo sapiens hsa-miR-1246 mature miRNA |
| Sequence | 11 - AAUGGAUUUUUGGAGCAGG - 29 |
| Evidence |
experimental
Illumina [1] |
| Database links |
|
| Predicted targets |
|
References
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