Accession
MI0006381
Symbol
HGNC:
MIR1246
Description
Homo sapiens
hsa-mir-1246 precursor miRNA mir-1246
Gene
family?
family?
RF03434;
mir-1246
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
MIR1246 is a type of microRNA that has been studied in relation to tumor invasion, lymph node metastasis, distant metastasis, and cancer stage. However, serum and urine levels of MIR1246 did not show any correlations with these factors (Table 2) [PMC7250935]. Despite this, MIR1246 has been found to have a specific target called early B cytokine 1 (EBF1) [PMC8258133]. It binds to the 3′UTR site of EBF1 and potentially regulates its expression. These findings suggest that MIR1246 may have a role in cancer progression through its interaction with EBF1. However, further research is needed to fully understand the functional significance of this interaction and its implications in cancer development and progression.
Literature search
83 open access papers mention hsa-mir-1246
(525 sentences)
(525 sentences)
Sequence
41973
reads,
1903
reads per million, 98 experiments
uguauccuugAAUGGAUUUUUGGAGCAGGaguggacaccugacccaaaggaaaucaauccauaggcuagcaau
(((..(((...((((((((((((..((((........))))..))))).......))))))))))...)))..
(((..(((...((((((((((((..((((........))))..))))).......))))))))))...)))..
Structure
-- -au ugA ------- AG agu ugu ccu AUGGAUU UUUGG CAGG g ||| ||| ||||||| ||||| |||| acg gga uaccuaa aaacc gucc g ua auc --- cuaaagg ca aca
Annotation confidence
Not enough data
Do you think this miRNA is real?
Genome context
chr2: 176600980-176601052 [-]
Disease association
hsa-mir-1246 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-1246
| Accession | MIMAT0005898 |
| Description | Homo sapiens hsa-miR-1246 mature miRNA |
| Sequence | 11 - AAUGGAUUUUUGGAGCAGG - 29 |
| Evidence |
experimental
Illumina [1] |
| Database links |
|
| Predicted targets |
|
References
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