Stem-loop cel-mir-1821

Accession

MI0007983

Description

Caenorhabditis elegans cel-mir-1821 precursor miRNA

Literature search

2 open access papers mention cel-mir-1821
(4 sentences)

Sequence

1867 reads, 11 reads per million, 14 experiments

auauguaguugguacaaguuUGCCCAACUUGCAGACUUUUCAAUuuucggcaaguggaauUGAGGUCUUAUAGUUAGGUAGAcauuuacuacaacuaauauaua
((((((((((((((...(((((((.((((...(((((..((((((((........)))))))))))))...)))).)))))))...)))..))))).)))))).

Structure

-      -     --   caa       C    UGC     UU        cgg 
 auaugu aguug  gua   guuUGCC AACU   AGACU  UCAAUuuu   c
 |||||| |||||  |||   ||||||| ||||   |||||  ||||||||    
 uauaua ucaac  cau   cAGAUGG UUGA   UCUGG  AGUuaagg   a
a      a     au   uua       A    UAU     --        uga 

Annotation confidence Low

Comments

This sequence was erroneously named mir-806 in [1].

Genome context

chrV: 3042530-3042633 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from cel-mir-1821

Mature cel-miR-1821-3p

• Accession: MIMAT0006588
• Description: Caenorhabditis elegans cel-miR-1821-3p mature miRNA
• Sequence: 61 - UGAGGUCUUAUAGUUAGGUAGA - 82
• Evidence: experimental ; 454 [1-2], Illumina [3,5], CLIPseq [4]

Mature cel-miR-1821-5p

• Accession: MIMAT0032034
• Description: Caenorhabditis elegans cel-miR-1821-5p mature miRNA
• Sequence: 21 - UGCCCAACUUGCAGACUUUUCAAU - 44
• Evidence: not_experimental

References

1. PubMed ID: 19460142
   Dynamic expression of small non-coding RNAs, including novel microRNAs and piRNAs/21U-RNAs, during Caenorhabditis elegans development
   Kato M, de Lencastre A, Pincus Z, Slack FJ
   Genome Biol (2009) 10:R54


2. PubMed ID: 20062054
   Comprehensive discovery of endogenous Argonaute binding sites in Caenorhabditis elegans
   "Zisoulis DG, Lovci MT, Wilbert ML, Hutt KR, Liang TY, Pasquinelli AE, Yeo GW"
   "Nat Struct Mol Biol (2010) 17:173-179


3. PubMed ID: 18392026
   Discovering microRNAs from deep sequencing data using miRDeep
   "Friedlander MR, Chen W, Adamidi C, Maaskola J, Einspanier R, Knespel S, Rajewsky N"
   "Nat Biotechnol (2008) 26:407-415


4. PubMed ID: 18042455
   Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2
   "Zhang L, Ding L, Cheung TH, Dong MQ, Chen J, Sewell AK, Liu X, Yates JR 3rd, Han M"
   "Mol Cell (2007) 28:598-613


5. PubMed ID: 21307183
   Improved annotation of C. elegans microRNAs by deep sequencing reveals structures associated with processing by Drosha and Dicer
   "Warf MB, Johnson WE, Bass BL"
   "RNA (2011) 17:563-577