Stem-loop hsv2-mir-H2

Accession

MI0010694

Description

Herpes Simplex Virus 2 hsv2-mir-H2 precursor miRNA

Sequence

ucggucgcgccugcccggcccagacucugugcuugggugucggUCUGAGCCUGGGUCAUGCGCGAccgg
.(((((((((.((((((((.((((((....((......)).)))))).))).))).)).))))))))).

Structure

u         c  -   -   c      cugu  uu 
 cggucgcgc ug ccc ggc cagacu    gc  g
 ||||||||| || ||| ||| ||||||    ||   
 gccAGCGCG AC GGG CCG GUCUgg    ug  g
g         U  U   U   A      ---c  ug 

Annotation confidence Not enough data

Comments

This sequence was named miR-III in [1], but is a clear homolog of miR-H2 in HSV-1.

Genome context

Unknown

Mature hsv2-miR-H2

• Accession: MIMAT0010205
• Description: Herpes Simplex Virus 2 hsv2-miR-H2 mature miRNA
• Sequence: 44 - UCUGAGCCUGGGUCAUGCGCGA - 65
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 20181707
   Numerous conserved and divergent microRNAs expressed by herpes simplex viruses 1 and 2
   "Jurak I, Kramer MF, Mellor JC, van Lint AL, Roth FP, Knipe DM, Coen DM"
   "J Virol (2010) 84:4659-4672


2. PubMed ID: 19019961
   Novel less-abundant viral microRNAs encoded by herpes simplex virus 2 latency-associated transcript and their roles in regulating ICP34.5 and ICP0 mRNAs
   "Tang S, Patel A, Krause PR"
   "J Virol (2009) 83:1433-1442