Stem-loop hsa-mir-500b

Accession

MI0015903

Symbol

HGNC: MIR500B

Description

Homo sapiens hsa-mir-500b precursor miRNA mir-500

Gene
family

RF01903; mir-500

Literature search

30 open access papers mention hsa-mir-500b
(66 sentences)

Sequence

11316 reads, 42.0 reads per million, 144 experiments

cccccucucUAAUCCUUGCUACCUGGGUGAGAGUgcuuucugaaugcAGUGCACCCAGGCAAGGAUUCUgcaaggggga
((((((..(.(((((((((...(((((((..(.(((.........))).).))))))))))))))))..)..)))))).

Structure

-      cu -U         UAC       AG G   uuu 
 cccccu  c  AAUCCUUGC   CUGGGUG  A Ugc   c
 ||||||  |  |||||||||   |||||||  | |||   u
 ggggga  g  UUAGGAACG   GACCCAC  U Acg   g
a      ac UC         ---       -G G   uaa 

Annotation confidence High

Genome context

chrX: 50010672-50010750 [+]

Clustered miRNAs

7 other miRNAs are < 10 kb from hsa-mir-500b

Disease association

hsa-mir-500b is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-500b-5p

• Accession: MIMAT0016925
• Description: Homo sapiens hsa-miR-500b-5p mature miRNA
• Sequence: 10 - UAAUCCUUGCUACCUGGGUGAGAGU - 34
• Evidence: experimental ; SOLiD [1], Illumina [2]

Mature hsa-miR-500b-3p

• Accession: MIMAT0027032
• Description: Homo sapiens hsa-miR-500b-3p mature miRNA
• Sequence: 48 - AGUGCACCCAGGCAAGGAUUCU - 69
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 19784364
   Ago2 immunoprecipitation identifies predicted microRNAs in human embryonic stem cells and neural precursors
   Goff LA, Davila J, Swerdel MR, Moore JC, Cohen RI, Wu H, Sun YE, Hart RP
   PLoS One (2009) 4:e7192


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45