Stem-loop bma-mir-5839

Accession

MI0023434

Description

Brugia malayi bma-mir-5839 precursor miRNA

Literature search

1 open access papers mention bma-mir-5839
(2 sentences)

Sequence

gugauaauuaacugcaaccaaaAGGAGUAAUAUUCUAACGUUGAGCaaaaauauacaaugCUUCGUAGAUUAUUACUCCCAAuggaagcagugagauagcaguau
((........(((((..(((...(((((((((.((((.((..(((((...........))))))))))).)))))))))...)))..)))))......)).....

Structure

-----  gauaauua     aa   aaA         U    A  UU     aaaa 
     gu        acugc  cca   GGAGUAAUA UCUA CG  GAGCa    u
     ||        |||||  |||   ||||||||| |||| ||  |||||    a
     cg        ugacg  ggu   CCUCAUUAU AGAU GC  UUCgu    u
uauga  --auagag     aa   AAC         U    -  --     aaca 

Annotation confidence Low

Comments

This microRNA was experimentally validated from deep sequencing libraries in the closely related species Brugia pahangi [1].

Genome context

Bmal_v3_scaffold153: 22289-22393 [+]

Clustered miRNAs

6 other miRNAs are < 10 kb from bma-mir-5839

Mature bma-miR-5839-3p

• Accession: MIMAT0026337
• Description: Brugia malayi bma-miR-5839-3p mature miRNA
• Sequence: 61 - CUUCGUAGAUUAUUACUCCCAA - 82
• Evidence: not_experimental

Mature bma-miR-5839-5p

• Accession: MIMAT0037477
• Description: Brugia malayi bma-miR-5839-5p mature miRNA
• Sequence: 23 - AGGAGUAAUAUUCUAACGUUGAGC - 46
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 22216965
   Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel
   Winter AD, Weir W, Hunt M, Berriman M, Gilleard JS, Devaney E, Britton C
   BMC Genomics (2012) 13:4


2. PubMed ID: 24824352
   Diversity and expression of microRNAs in the filarial parasite, Brugia malayi
   Poole CB, Gu W, Kumar S, Jin J, Davis PJ, Bauche D, McReynolds LA
   PLoS One (2014) 9:e96498