Stem-loop bma-mir-5841

Accession

MI0023437

Description

Brugia malayi bma-mir-5841 precursor miRNA

Sequence

59000 reads, 901.0 reads per million, 20 experiments

uaccuacgugaaguauucugaaugcuguaauuguuuuauuuaaauuaugggaguaAUGGCCUGGAUUUUGUCCAAAGcguuguaauacagcUUUGGCACCAUUCAGACCACUacaccuaauuucaccuuuauacc
.......((((((((((...))))))((((((..........))))))(((.(((.(((.((((((..((.(((((((((......)).)))))))))..)))))).))).))).)))....)))).........

Structure

--uaccuac    aguauucugaaugcuguaauuguuuuauuuaaauuau   a   A   C      UU  U       -  ug 
         guga                                     ggg gua UGG CUGGAU  UG CCAAAGc gu  u
         ||||                                     ||| ||| ||| ||||||  || ||||||| ||   
         cacu                                     ucc caU ACC GACUUA  AC GGUUUcg ca  a
ccauauuuc    ---------------------------------uuaa   a   C   A      CC  -       a  ua 

Annotation confidence High

Comments

This microRNA was experimentally validated from deep sequencing libraries in the closely related species Brugia pahangi [1].

Genome context

Bmal_v3_scaffold435: 2745-2879 [-]

Clustered miRNAs

3 other miRNAs are < 10 kb from bma-mir-5841

Mature bma-miR-5841-5p

• Accession: MIMAT0026339
• Description: Brugia malayi bma-miR-5841-5p mature miRNA
• Sequence: 56 - AUGGCCUGGAUUUUGUCCAAAG - 77
• Evidence: not_experimental

Mature bma-miR-5841-3p

• Accession: MIMAT0037478
• Description: Brugia malayi bma-miR-5841-3p mature miRNA
• Sequence: 92 - UUUGGCACCAUUCAGACCACU - 112
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 22216965
   Diversity in parasitic nematode genomes: the microRNAs of Brugia pahangi and Haemonchus contortus are largely novel
   Winter AD, Weir W, Hunt M, Berriman M, Gilleard JS, Devaney E, Britton C
   BMC Genomics (2012) 13:4


2. PubMed ID: 24824352
   Diversity and expression of microRNAs in the filarial parasite, Brugia malayi
   Poole CB, Gu W, Kumar S, Jin J, Davis PJ, Bauche D, McReynolds LA
   PLoS One (2014) 9:e96498