miRBase entry: hsa-mir-486-2

Stem-loop hsa-mir-486-2

Accession

MI0023622

Symbol

HGNC: MIR486-2

Description

Homo sapiens hsa-mir-486-2 precursor miRNA mir-486

Gene
family?

RF00784; mir-486

Literature search

182 open access papers mention hsa-mir-486-2
(1116 sentences)

Sequence

130645 reads, 753 reads per million, 106 experiments

UCCUGUACUGAGCUGCCCCGAGcugggcagcaugaagggccuCGGGGCAGCUCAGUACAGGAUg
((((((((((((((((((((((((...((...))...)).))))))))))))))))))))))..

Structure

--                      -  ggg  g 
  UCCUGUACUGAGCUGCCCCGAG cu   ca  
  |||||||||||||||||||||| ||   || c
  AGGACAUGACUCGACGGGGCuc gg   gu  
gU                      c  gaa  a

Annotation confidence Medium

Do you think this miRNA is real?

Genome context

chr8: 41660444-41660507 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-486-2

Name	Accession	Chromosome	Start	End	Strand	Confidence

Disease association

hsa-mir-486-2 is associated with one or more human diseases in the Human microRNA Disease Database

Disease	Description	Category	PubMed ID

Database links

Mature hsa-miR-486-5p

Accession	MIMAT0002177
Description	Homo sapiens hsa-miR-486-5p mature miRNA
Sequence	1 - UCCUGUACUGAGCUGCCCCGAG - 22
Evidence	experimental Illumina [1]
Database links
Predicted targets

Mature hsa-miR-486-3p

Accession	MIMAT0004762
Description	Homo sapiens hsa-miR-486-3p mature miRNA
Sequence	43 - CGGGGCAGCUCAGUACAGGAU - 63
Evidence	experimental Illumina [1]
Database links
Predicted targets

References

PubMed ID: 23034410
Birth and expression evolution of mammalian microRNA genes
"Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
"Genome Res (2013) 23:34-45