miRBase entry: hsa-miR-10a-5p

Mature hsa-miR-10a-5p

Accession MIMAT0000253
Description hsa-miR-10a-5p mature miRNA
Hairpins
Sequence UACCCUGUAGAUCCGAAUUUGUG
Evidence experimental
cloned [2-3]
Database links
Predicted targets


QuickGo Function

QuickGO is a fast web-based browser of the Gene Ontology and Gene Ontology annotation data.

Qualifier GO term Evidence Reference Annotation Extension
enables GO:0003730
mRNA 3'-UTR binding
ECO:0000314
direct assay evidence used in manual assertion
PMID:22996586
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:22955733 has_input
UniProtKB:P17948
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:22996586 has_input
UniProtKB:P54764
enables GO:1903231
mRNA base-pairing translational repressor activity
ECO:0000314
direct assay evidence used in manual assertion
PMID:25068583 has_input
UniProtKB:Q92908
involved_in GO:0007162
negative regulation of cell adhesion
ECO:0000314
direct assay evidence used in manual assertion
PMID:22996586
involved_in GO:0030335
positive regulation of cell migration
ECO:0000314
direct assay evidence used in manual assertion
PMID:22996586
involved_in GO:0030949
positive regulation of vascular endothelial growth factor receptor signaling pathway
ECO:0000316
genetic interaction evidence used in manual assertion
PMID:22955733 occurs_in
CL:0002618
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:22955733 has_input
UniProtKB:P17948
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:22996586 has_input
UniProtKB:P54764
involved_in GO:0035195
miRNA-mediated post-transcriptional gene silencing
ECO:0000314
direct assay evidence used in manual assertion
PMID:25068583 has_input
UniProtKB:Q92908
involved_in GO:0090050
positive regulation of cell migration involved in sprouting angiogenesis
ECO:0000316
genetic interaction evidence used in manual assertion
PMID:22955733 occurs_in
CL:0002618
involved_in GO:0110023
negative regulation of cardiac muscle myoblast proliferation
ECO:0000314
direct assay evidence used in manual assertion
PMID:25068583
involved_in GO:1902807
negative regulation of cell cycle G1/S phase transition
ECO:0000315
mutant phenotype evidence used in manual assertion
PMID:25068583 has_input
UniProtKB:P12004
involved_in GO:1902807
negative regulation of cell cycle G1/S phase transition
ECO:0000315
mutant phenotype evidence used in manual assertion
PMID:25068583 has_input
UniProtKB:Q01094
involved_in GO:1903589
positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
ECO:0000316
genetic interaction evidence used in manual assertion
PMID:22955733 occurs_in
CL:0002618
located_in GO:0005615
extracellular space
ECO:0007005
high throughput direct assay evidence used in manual assertion
PMID:26646931 part_of
UBERON:0001969

StarBase

MicroRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.

Target Gene ID Target Gene Name Number of supporting experiments Number of target-predicting programs Maximum number of target sites Chromosome Target-predicting region start Target-predicting region end Strand

miR2Disease

A manually curated database, aimed at providing a comprehensive resource of miRNA deregulation in various human diseases.

Click here for more information and to obtain references for the studies.

Disease Differential expression Experiment Year Study