Mature hsa-miR-125a-5p
| Accession | MIMAT0000443 |
| Description | hsa-miR-125a-5p mature miRNA |
| Hairpins | |
| Sequence | UCCCUGAGACCCUUUAACCUGUGA |
| Evidence |
experimental
cloned [2-3] |
| Database links |
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| Predicted targets |
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QuickGo Function
QuickGO is a fast web-based browser of the Gene Ontology and Gene Ontology annotation data.
| Qualifier | GO term | Evidence | Reference | Annotation Extension |
|---|---|---|---|---|
| acts_upstream_of | GO:0001960 negative regulation of cytokine-mediated signaling pathway |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:30089723 | has_input UniProtKB:Q14005-PRO_0000015412 |
| acts_upstream_of | GO:1902564 negative regulation of neutrophil activation |
ECO:0000250 sequence similarity evidence used in manual assertion |
PMID:30089723 | occurs_in UBERON:0002048 |
| acts_upstream_of | GO:1904893 negative regulation of receptor signaling pathway via STAT |
ECO:0000316 genetic interaction evidence used in manual assertion |
PMID:30670152 | has_input UniProtKB:P40763 |
| acts_upstream_of_or_within | GO:0070104 negative regulation of interleukin-6-mediated signaling pathway |
ECO:0000316 genetic interaction evidence used in manual assertion |
PMID:30670152 | occurs_in CL:0002618 |
| acts_upstream_of_or_within | GO:1904995 negative regulation of leukocyte adhesion to vascular endothelial cell |
ECO:0000316 genetic interaction evidence used in manual assertion |
PMID:30670152 | occurs_in CL:0000576 |
| enables | GO:0003730 mRNA 3'-UTR binding |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:30089723 | has_input UniProtKB:Q14005 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:20190813 | has_input UniProtKB:P38936 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:22357933 | has_input UniProtKB:Q13485 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:26563755 | has_input UniProtKB:P08887 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:27252357 | has_input UniProtKB:Q9NR61 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28467514 | has_input UniProtKB:O14733 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:30089723 | has_input UniProtKB:Q14005 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:30670152 | has_input UniProtKB:P08887 |
| enables | GO:1903231 mRNA base-pairing translational repressor activity |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:30670152 | has_input UniProtKB:P40763 |
| involved_in | GO:0010628 positive regulation of gene expression |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25116893 | has_input UniProtKB:P42574 |
| involved_in | GO:0010629 negative regulation of gene expression |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:25116893 | has_input UniProtKB:P10415 |
| involved_in | GO:0016525 negative regulation of angiogenesis |
ECO:0000315 mutant phenotype evidence used in manual assertion |
PMID:25116893 | occurs_in CL:0002618 |
| involved_in | GO:0032699 negative regulation of interleukin-16 production |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:30089723 | occurs_in CL:0000576 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0007005 high throughput direct assay evidence used in manual assertion |
PMID:18320040 | has_input UniProtKB:P15692 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:20190813 | has_input UniProtKB:P38936 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:24759737 | has_input UniProtKB:P01579 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:26563755 | has_input UniProtKB:P08887 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:27252357 | has_input UniProtKB:Q9NR61 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:28467514 | has_input UniProtKB:O14733 |
| involved_in | GO:0035195 miRNA-mediated post-transcriptional gene silencing |
ECO:0000314 direct assay evidence used in manual assertion |
PMID:30089723 | has_input UniProtKB:Q14005 |
StarBase
MicroRNA-mRNA interaction maps from Argonaute CLIP-Seq and Degradome-Seq data.
| Target Gene ID | Target Gene Name | Number of supporting experiments | Number of target-predicting programs | Maximum number of target sites | Chromosome | Target-predicting region start | Target-predicting region end | Strand |
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miR2Disease
A manually curated database, aimed at providing a comprehensive resource of miRNA deregulation in various human diseases.
Click here for more information and to obtain references for the studies.
| Disease | Differential expression | Experiment | Year | Study |
|---|
