Accession
MI0000077
Symbol
HGNC:
MIR21
Description
Homo sapiens
hsa-mir-21 precursor miRNA mir-21
Gene
family?
family?
RF00658;
mir-21
Literature search
1559 open access papers mention hsa-mir-21
(13078 sentences)
(13078 sentences)
Sequence
6832853
reads,
24235
reads per million, 159 experiments
ugucgggUAGCUUAUCAGACUGAUGUUGAcuguugaaucucauggCAACACCAGUCGAUGGGCUGUcugaca
((((((((((((((((.(((((.(((((.((((.((...))))))))))).)))))))))))))))))))))
((((((((((((((((.(((((.(((((.((((.((...))))))))))).)))))))))))))))))))))
Structure
A A A u a
ugucgggUAGCUUAUC GACUG UGUUG cugu ga
|||||||||||||||| ||||| ||||| |||| || u
acagucUGUCGGGUAG CUGAC ACAAC ggua cu
- C - - c
Annotation confidence
High
Do you think this miRNA is real?
Comments
Mourelatos et al. named this sequence miR-21 precursor-17 and also reported the exact reverse complement of this predicted stem-loop sequence and erroneously assigned the name miR-104 [2].
Genome context
chr17: 59841266-59841337 [+]
Disease association
hsa-mir-21 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Biological pathways
hsa-mir-21 is involved in one or more biological pathways:
(Source: Reactome)
(Source: Reactome)
Biological reactions
hsa-mir-21 is involved in one or more regulation/signalling events:
(Source: Reactome)
(Source: Reactome)
Database links
Mature hsa-miR-21-5p
| Accession | MIMAT0000076 |
| Description | Homo sapiens hsa-miR-21-5p mature miRNA |
| Sequence | 8 - UAGCUUAUCAGACUGAUGUUGA - 29 |
| Evidence |
experimental
cloned [1-3,6-9], Northern [1,5], Illumina [10] |
| Database links |
|
| Predicted targets |
|
Mature hsa-miR-21-3p
| Accession | MIMAT0004494 |
| Description | Homo sapiens hsa-miR-21-3p mature miRNA |
| Sequence | 46 - CAACACCAGUCGAUGGGCUGU - 66 |
| Evidence |
experimental
cloned [8-9] |
| Database links |
|
| Predicted targets |
|
References
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