miRBase entry: hsa-mir-182

Stem-loop hsa-mir-182


Accession
MI0000272
Symbol
HGNC: MIR182
Description
Homo sapiens hsa-mir-182 precursor miRNA
Gene family
MIPF0000116; mir-182

Literature search
290 open access papers mention hsa-mir-182
(2366 sentences)

Sequence

86555 reads, 521 reads per million, 146 experiments
gagcugcuugccuccccccguuUUUGGCAAUGGUAGAACUCACACUggugagguaacaggauccggUGGUUCUAGACUUGCCAACUAuggggcgaggacucagccggcac
..((((((.(((((.((((((..(((((((...((((((...((((((..............))))))))))))...)))))))..)))))).)))).)..)).))))..

Structure
ga    -  -u -    c      uU       UGG      UCA      ugaggu 
  gcug cu  g ccuc ccccgu  UUGGCAA   UAGAAC   CACUgg      a
  |||| ||  | |||| ||||||  |||||||   ||||||   ||||||       
  cggc ga  c ggag gggguA  AACCGUU   AUCUUG   GUggcc      a
ca    c  cu a    c      UC       CAG      ---      uaggac 


Annotation confidence High
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Genome context
chr7: 129770383-129770492 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from hsa-mir-182
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-182 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-182-5p

Accession MIMAT0000259
Description Homo sapiens hsa-miR-182-5p mature miRNA
Sequence 23 - UUUGGCAAUGGUAGAACUCACACU - 46
Evidence experimental
cloned [2-3]
Database links
Predicted targets

Mature hsa-miR-182-3p

Accession MIMAT0000260
Description Homo sapiens hsa-miR-182-3p mature miRNA
Sequence 67 - UGGUUCUAGACUUGCCAACUA - 87
Evidence not_experimental

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  3. PubMed ID: 12624257
    Vertebrate microRNA genes
    "Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP"
    "Science (2003) 299:1540