Stem-loop sequence hsa-mir-182

Accession

MI0000272 (change log)

Previous IDs

hsa-mir-182-as

Symbol

HGNC:MIR182

Description

Homo sapiens miR-182 stem-loop

Gene family

MIPF0000116; mir-182

Literature search

290 open access papers mention hsa-mir-182
(2346 sentences)

Stem-loop

   ga    -  --ug    c      uu       u -g      uca      ugaggu 
5'   gcug cu    ccuc ccccgu  uuggcaa g  uagaac   cacugg      a
     |||| ||    |||| ||||||  ||||||| |  ||||||   ||||||       
3'   cggc ga    ggag ggggua  aaccguu c  aucuug   guggcc      a
   ca    c  cuca    c      uc       - ag      ---      uaggac 

Deep sequencing

492142 reads, 1.32e+03 reads per million, 156 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chr7: 129770383-129770492 [-]
• Overlapping transcripts:

  antisense

  OTTHUMT00000349347 ; KLHDC10-001; 3'UTR (exon 10)

  ENST00000335420 ; KLHDC10-001; 3'UTR (exon 10)

Clustered miRNAs

< 10kb from hsa-mir-182

• hsa-mir-183: chr7: 129774905-129775014 [-]
• hsa-mir-96: chr7: 129774692-129774769 [-]
• hsa-mir-182: chr7: 129770383-129770492 [-]

Database links

• EntrezGene:MIR182
• HGNC:MIR182
• RNAcentral:URS000075B66E_9606
• miRBase Tracker:MI0000272

Mature sequence hsa-miR-182-5p

• Accession: MIMAT0000259
• Previous IDs: hsa-miR-182
• Sequence: 23 - uuuggcaaugguagaacucacacu - 46
• Deep sequencing: 491694 reads, 156 experiments
• Evidence: experimental; cloned [2-3]
• Database links:
  • RNAcentral:URS00001CC379_9606
• Predicted targets:
  • TargetMiner:hsa-miR-182-5p
  • TargetScanVert:hsa-miR-182-5p
  • miRDB:hsa-miR-182-5p
  • microrna.org:hsa-miR-182-5p

Mature sequence hsa-miR-182-3p

• Accession: MIMAT0000260
• Previous IDs: hsa-miR-182*
• Sequence: 67 - ugguucuagacuugccaacua - 87
• Deep sequencing: 437 reads, 67 experiments
• Evidence: by similarity; MI0001368
• Predicted targets:
  • TargetMiner:hsa-miR-182-3p
  • TargetScanVert:hsa-miR-182-3p
  • miRDB:hsa-miR-182-3p
  • microrna.org:hsa-miR-182-3p

References

1. PMID:12624257 "Vertebrate microRNA genes" Lim LP, Glasner ME, Yekta S, Burge CB, Bartel DP Science. 299:1540(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17616659 "Patterns of known and novel small RNAs in human cervical cancer" Lui WO, Pourmand N, Patterson BK, Fire A Cancer Res. 67:6031-6043(2007).