Stem-loop hsa-mir-374a

Accession

MI0000782

Symbol

HGNC: MIR374A

Description

Homo sapiens hsa-mir-374a precursor miRNA

Literature search

67 open access papers mention hsa-mir-374a
(407 sentences)

Sequence

165950 reads, 581 reads per million, 146 experiments

uacaucggccaUUAUAAUACAACCUGAUAAGUGuuauagcaCUUAUCAGAUUGUAUUGUAAUUgucugugua
(((((.(((.((((((((((((.(((((((((((....))))))))))).)))))))))))).))).)))))

Structure

     c   c            C           u 
uacau ggc aUUAUAAUACAA CUGAUAAGUGu a
||||| ||| |||||||||||| |||||||||||  
augug cug UAAUGUUAUGUU GACUAUUCacg u
     u   U            A           a 

Annotation confidence High

Genome context

chrX: 74287286-74287357 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from hsa-mir-374a

Disease association

hsa-mir-374a is associated with one or more human diseases in the Human microRNA Disease Database

Mature hsa-miR-374a-5p

• Accession: MIMAT0000727
• Description: Homo sapiens hsa-miR-374a-5p mature miRNA
• Sequence: 12 - UUAUAAUACAACCUGAUAAGUG - 33
• Evidence: experimental ; cloned [1-4], Northern [1]

Mature hsa-miR-374a-3p

• Accession: MIMAT0004688
• Description: Homo sapiens hsa-miR-374a-3p mature miRNA
• Sequence: 42 - CUUAUCAGAUUGUAUUGUAAUU - 63
• Evidence: experimental ; cloned [3]

References

1. PubMed ID: 15183728
   Human embryonic stem cells express a unique set of microRNAs
   "Suh MR, Lee Y, Kim JY, Kim SK, Moon SH, Lee JY, Cha KY, Chung HM, Yoon HS, Moon SY, Kim VN, Kim KS"
   "Dev Biol (2004) 270:488-498


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 17616659
   Patterns of known and novel small RNAs in human cervical cancer
   "Lui WO, Pourmand N, Patterson BK, Fire A"
   "Cancer Res (2007) 67:6031-6043


4. PubMed ID: 16274478
   Identification of clustered microRNAs using an ab initio prediction method
   Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
   BMC Bioinformatics (2005) 6:267