Accession
MI0001641
Symbol
HGNC:
MIR429
Description
Homo sapiens
hsa-mir-429 precursor miRNA mir-8
Gene
family?
family?
RF00241;
mir-8
Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?
WARNING: This summary was generated by AI. MIR429 is a microRNA that has been identified as a regulator of cellular processes in various carcinomas, including those of the endometrial, prostate, and breast tissues [PMC9866967]. It is one of several microRNAs, including MIR200A, MIR200B, MIR200C, and MIR25 that have been previously reported in the literature [PMC6701281]. Specifically, MIR429 has been shown to influence the proliferation and invasion capabilities of cancer cells in these carcinomas [PMC9866967]. This suggests that MIR429 may play a significant role in cancer progression and could potentially serve as a target for therapeutic intervention.
Literature search
481 open access papers mention hsa-mir-429
(1440 sentences)
(1440 sentences)
Sequence
22336
reads,
48.0
reads per million, 152 experiments
cgccggccgaugggcGUCUUACCAGACAUGGUUAGACcuggcccucugucUAAUACUGUCUGGUAAAACCGUccauccgcugc
...((((.((((((((..((((((((((..(((((((..........)))))))..))))))))))...)))))))).)))).
...((((.((((((((..((((((((((..(((((((..........)))))))..))))))))))...)))))))).)))).
Structure
cgc c -UC UG cugg cggc gaugggcG UUACCAGACA GUUAGAC c |||| |||||||| |||||||||| ||||||| gucg cuaccUGC AAUGGUCUGU UAAUcug c --c c CAA CA ucuc
Annotation confidence
High
Do you think this miRNA is real?
Comments
Xie et al. [1] refer to this sequence by the internal identifier MIR201. The sequence is unrelated to mouse mir-201 (MIR:MI0000244).
Genome context
chr1: 1169005-1169087 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from hsa-mir-429
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Disease association
hsa-mir-429 is associated with one or more human diseases in the Human microRNA Disease Database
| Disease | Description | Category | PubMed ID |
|---|
Database links
Mature hsa-miR-429-5p
| Accession | MIMAT0060796 |
| Description | Homo sapiens hsa-miR-429-5p mature miRNA |
| Sequence | 16 - GUCUUACCAGACAUGGUUAGAC - 37 |
| Evidence |
experimental
cloned [1-4] |
Mature hsa-miR-429-3p
| Accession | MIMAT0001536 |
| Description | Homo sapiens hsa-miR-429-3p mature miRNA |
| Sequence | 51 - UAAUACUGUCUGGUAAAACCGU - 72 |
| Evidence |
experimental
cloned [1-4] |
| Database links |
|
| Predicted targets |
|
References
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