miRBase entry: hsa-mir-542

Stem-loop hsa-mir-542


Accession
MI0003686
Symbol
HGNC: MIR542
Description
Homo sapiens hsa-mir-542 precursor miRNA
Gene family
MIPF0000185; mir-542

Literature search
52 open access papers mention hsa-mir-542
(251 sentences)

Sequence

41785 reads, 402 reads per million, 112 experiments
cagaucucagacaucUCGGGGAUCAUCAUGUCACGAGAuaccagugugcacuUGUGACAGAUUGAUAACUGAAAggucugggagccacucaucuuca
....((((((((...((((..((((...(((((((((.(((....)))..)))))))))...))))..))))...))))))))..............

Structure
----------caga        auc    GG    UCA         -A   c 
              ucucagac   UCGG  AUCA   UGUCACGAG  uac a
              ||||||||   ||||  ||||   |||||||||  |||  
              agggucug   AGUC  UAGU   ACAGUGUuc  gug g
acuucuacucaccg        gAA    AA    UAG         ac   u 


Annotation confidence High
Do you think this miRNA is real?
Comments
The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [2].

Genome context
chrX: 134541341-134541437 [-]
Clustered miRNAs
5 other miRNAs are < 10 kb from hsa-mir-542
Name Accession Chromosome Start End Strand Confidence




Disease association
hsa-mir-542 is associated with one or more human diseases in the Human microRNA Disease Database
Disease Description Category PubMed ID


Database links

Mature hsa-miR-542-5p

Accession MIMAT0003340
Description Homo sapiens hsa-miR-542-5p mature miRNA
Sequence 16 - UCGGGGAUCAUCAUGUCACGAGA - 38
Evidence experimental
cloned [1-3]
Database links
Predicted targets

Mature hsa-miR-542-3p

Accession MIMAT0003389
Description Homo sapiens hsa-miR-542-3p mature miRNA
Sequence 53 - UGUGACAGAUUGAUAACUGAAA - 74
Evidence experimental
cloned [1-2]
Database links
Predicted targets

References

  1. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  2. PubMed ID: 17616659
    Patterns of known and novel small RNAs in human cervical cancer
    "Lui WO, Pourmand N, Patterson BK, Fire A"
    "Cancer Res (2007) 67:6031-6043

  3. PubMed ID: 16274478
    Identification of clustered microRNAs using an ab initio prediction method
    Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M
    BMC Bioinformatics (2005) 6:267