miRBase entry: mmu-mir-669a-1

Stem-loop mmu-mir-669a-1


Accession
MI0004523
Symbol
MGI: Mir669a-1
Description
Mus musculus mmu-mir-669a-1 precursor miRNA
Gene family
MIPF0000316; mir-467

Literature search
15 open access papers mention mmu-mir-669a-1
(22 sentences)

Sequence

23872 reads, 316 reads per million, 101 experiments
uguaugugcauguguguauAGUUGUGUGUGCAUGUUCAUGUCUauauuugaauauACAUAACAUACACACACACGUAUaaacgcaagcacacauaca
(((((((((.(((((.((((..((((((((.(((((.((((.(((......))).))))))))).))))))))..)))).))))).)))))..))))

Structure
    --     a     g    GU        C     C    C   au 
ugua  ugugc ugugu uauA  UGUGUGUG AUGUU AUGU Uau  u
||||  ||||| ||||| ||||  |||||||| ||||| |||| |||   
acau  acacg acgca aUAU  ACACACAC UACAA UACA aua  u
    ac     a     a    GC        A     -    u   ag 


Annotation confidence High
Do you think this miRNA is real?
Comments
The sequence of miR-669a-1 is of low complexity. The sequence maps exactly to several genomic positions, and many more with 1 or 2 substitutions. Confidence in this miRNA might therefore be reduced.

Genome context
chr2: 10476853-10476949 [+]
Clustered miRNAs
31 other miRNAs are < 10 kb from mmu-mir-669a-1
Name Accession Chromosome Start End Strand Confidence




Database links

Mature mmu-miR-669a-5p

Accession MIMAT0003477
Description Mus musculus mmu-miR-669a-5p mature miRNA
Sequence 20 - AGUUGUGUGUGCAUGUUCAUGUCU - 43
Evidence experimental
Illumina [1]
Database links
Predicted targets

Mature mmu-miR-669a-3p

Accession MIMAT0017243
Description Mus musculus mmu-miR-669a-3p mature miRNA
Sequence 56 - ACAUAACAUACACACACACGUAU - 78
Evidence experimental
Illumina [1]
Database links
Predicted targets

References

  1. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  2. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  3. PubMed ID: 20668074
    Identification and analysis of expression of novel microRNAs of murine gammaherpesvirus 68
    "Zhu JY, Strehle M, Frohn A, Kremmer E, Hofig KP, Meister G, Adler H"
    "J Virol (2010) 84:10266-10275

  4. PubMed ID: 16582102
    The expression profile of microRNAs in mouse embryos
    "Mineno J, Okamoto S, Ando T, Sato M, Chono H, Izu H, Takayama M, Asada K, Mirochnitchenko O, Inouye M, Kato I"
    "Nucleic Acids Res (2006) 34:1765-1771