Accession
MI0004702
Symbol
MGI:
Mir500
Description
Mus musculus
mmu-mir-500 precursor miRNA mir-500
Gene
family?
family?
RF01903;
mir-500
Literature search
6 open access papers mention mmu-mir-500
(9 sentences)
(9 sentences)
Sequence
15961
reads,
116
reads per million, 103 experiments
cuccucugcucccccucucuAAUCCUUGCUAUCUGGGUGCUUAGUgcuaucucaaugcAAUGCACCUGGGCAAGGGUUCAgagaaggugagc
.......((((.((.((((((((((((((...((((((((....(((.........)))..))))))))))))))))).))))).)).))))
.......((((.((.((((((((((((((...((((((((....(((.........)))..))))))))))))))))).))))).)).))))
Structure
cuccucu c c - UAU UUAG uau
gcuc cc ucucu AAUCCUUGC CUGGGUGC Ugc c
|||| || ||||| ||||||||| |||||||| ||| u
cgag gg agagA UUGGGAACG GGUCCACG Acg c
------- u a C --- --UA uaa
Annotation confidence
High
Do you think this miRNA is real?
Comments
Mouse miR-500 was identified independently by two groups. Wheeler et al cloned a mature product with the same length as the human ortholog (MIR:MI0003184) [1]. Mineno et al report a shorter mature product with 1 additional base at the 5' end and 3 fewer at the 3' end (AAUGCACCUGGGCAAGGGUU), referred to as miR-500b in [2]. The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The 5' end of the miRNA may be offset with respect to previous annotations.
Genome context
chrX: 7237683-7237774 [-]
Clustered miRNAs
2 other miRNAs are < 10 kb from mmu-mir-500
| Name | Accession | Chromosome | Start | End | Strand | Confidence |
|---|
Database links
Mature mmu-miR-500-5p
| Accession | MIMAT0017258 |
| Description | Mus musculus mmu-miR-500-5p mature miRNA |
| Sequence | 21 - AAUCCUUGCUAUCUGGGUGCUUAGU - 45 |
| Evidence |
experimental
454 [5], Illumina [6] |
| Database links |
|
| Predicted targets |
|
Mature mmu-miR-500-3p
| Accession | MIMAT0003507 |
| Description | Mus musculus mmu-miR-500-3p mature miRNA |
| Sequence | 59 - AAUGCACCUGGGCAAGGGUUCA - 80 |
| Evidence |
experimental
cloned [1,3], insitu [1], Northern [1], MPSS [2], Illumina [4,6] |
| Database links |
|
| Predicted targets |
|
References
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