Stem-loop aae-mir-277

Accession

MI0013435

Description

Aedes aegypti aae-mir-277 precursor miRNA

Gene family

MIPF0000156; mir-277

Literature search

1 open access papers mention aae-mir-277
(1 sentences)

Sequence

18778 reads, 956 reads per million, 2 experiments

uaguuuuggagugCGUGUCAGAAGUGCAUUUACAuagguauuucccguuuagcaguauuugUAAAUGCACUAUCUGGUACGACauuccagaauca
..((((((((((((((((((((((((((((((((..((((((.(.......).)))))))))))))))))).))))))))).)))))))))))..

Structure

ua           -         -            ua      u cc 
  guuuuggagug CGUGUCAGA AGUGCAUUUACA  gguauu c  g
  ||||||||||| ||||||||| ||||||||||||  |||||| |  u
  uaagaccuuaC GCAUGGUCU UCACGUAAAUgu  uuauga g  u
ac           A         A            --      c au 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.265: 508799-508893 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from aae-mir-277

Mature aae-miR-277-5p

• Accession: MIMAT0014210
• Description: Aedes aegypti aae-miR-277-5p mature miRNA
• Sequence: 14 - CGUGUCAGAAGUGCAUUUACA - 34
• Evidence: experimental ; Illumina [2]

Mature aae-miR-277-3p

• Accession: MIMAT0014211
• Description: Aedes aegypti aae-miR-277-3p mature miRNA
• Sequence: 62 - UAAAUGCACUAUCUGGUACGAC - 83
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119